Detailed information of TA system TA053152

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1054780..1054960
• Replicon: chromosome
• Accession: NZ_CP010998
• Organism: Staphylococcus aureus strain FORC_012 isolate human sputum

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: FORC12_RS15120
• Protein ID: WP_001801861.1
• Coordinates: 1054780..1054875 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1054903..1054960 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FORC12_RS05225	1049821..1050447	+	627	WP_000669021.1	hypothetical protein	-
FORC12_RS05230	1050488..1050829	+	342	WP_000627547.1	DUF3969 family protein	-
FORC12_RS05235	1050930..1051502	+	573	WP_000414206.1	hypothetical protein	-
FORC12_RS05240	1051700..1052257	-	558	WP_000864139.1	ImmA/IrrE family metallo-endopeptidase	-
FORC12_RS05250	1052628..1052804	-	177	WP_000375476.1	hypothetical protein	-
FORC12_RS05255	1052815..1053198	-	384	WP_000070811.1	hypothetical protein	-
FORC12_RS05260	1053883..1054329	-	447	WP_000747802.1	DUF1433 domain-containing protein	-
FORC12_RS15120	1054780..1054875	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1054903..1054960	-	58	-	-	Antitoxin
FORC12_RS05270	1054998..1055099	+	102	WP_001791232.1	hypothetical protein	-
FORC12_RS14410	1055077..1055259	-	183	Protein_1020	transposase	-
FORC12_RS05275	1055447..1055821	-	375	WP_000695818.1	DUF1433 domain-containing protein	-
FORC12_RS05280	1055843..1056190	-	348	WP_001566695.1	DUF1433 domain-containing protein	-
FORC12_RS05285	1056427..1056843	-	417	WP_020978241.1	DUF1433 domain-containing protein	-
FORC12_RS05290	1057490..1058608	-	1119	WP_000072558.1	restriction endonuclease subunit S	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA / selk	1025245..1091073	65828

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T53152 WP_001801861.1 NZ_CP010998:1054780-1054875 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T53152 NZ_CP010998:1054780-1054875 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT53152 NZ_CP010998:c1054960-1054903 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin