53136

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 358344..359044 Replicon chromosome
Accession NZ_CP010979
Organism Pseudomonas putida S13.1.2

Toxin (Protein)


Gene name mqsR Uniprot ID A0A0C5RRJ0
Locus tag N805_RS01405 Protein ID WP_026034591.1
Coordinates 358344..358640 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A0C5S3M0
Locus tag N805_RS01410 Protein ID WP_026034592.1
Coordinates 358643..359044 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N805_RS01380 353638..354831 - 1194 WP_026034590.1 efflux RND transporter periplasmic adaptor subunit -
N805_RS01385 355057..355506 - 450 WP_019472600.1 azurin -
N805_RS01390 355727..356203 + 477 WP_019472601.1 sigma-70 family RNA polymerase sigma factor -
N805_RS01395 356372..356851 + 480 WP_019472602.1 hypothetical protein -
N805_RS01400 356924..358249 + 1326 WP_019472603.1 MFS transporter -
N805_RS01405 358344..358640 + 297 WP_026034591.1 type II toxin-antitoxin system MqsR family toxin Toxin
N805_RS01410 358643..359044 + 402 WP_026034592.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
N805_RS01415 359116..360798 - 1683 WP_080956764.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
N805_RS01420 361331..362080 + 750 WP_028613363.1 electron transfer flavoprotein subunit beta/FixA family protein -
N805_RS01425 362081..363010 + 930 WP_028613362.1 FAD-binding protein -
N805_RS01430 363086..363907 + 822 WP_019472048.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-96)

Antitoxin

Zinc finger, MqsA-type

(3-46)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11052.96 Da        Isoelectric Point: 9.7758

>T53136 WP_026034591.1 NZ_CP010979:358344-358640 [Pseudomonas putida S13.1.2]
MEKRTPHCPLERVKVLAAARRISPTGAALRGARALGMDYPGMLEVISSLERTDFYKSMTSHMDHRVWQDVYRPLTAIGYV
YLKVSVVDDVLIVSFKGL

Download         Length: 297 bp

>T53136 NZ_CP010979:358344-358640 [Pseudomonas putida S13.1.2]
ATGGAAAAGAGAACGCCTCACTGTCCGCTGGAACGGGTAAAAGTCTTGGCTGCTGCAAGGCGCATCAGCCCTACAGGCGC
TGCACTGAGAGGCGCCAGAGCGCTGGGAATGGATTATCCGGGCATGCTTGAAGTGATCTCCAGTTTGGAGCGCACTGATT
TTTACAAGAGCATGACCAGTCATATGGATCACCGGGTTTGGCAGGACGTCTATCGTCCGCTTACAGCAATTGGGTACGTT
TATCTGAAAGTGTCCGTGGTAGACGACGTGCTCATCGTGTCTTTCAAGGGGTTGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14548.56 Da        Isoelectric Point: 4.7551

>AT53136 WP_026034592.1 NZ_CP010979:358643-359044 [Pseudomonas putida S13.1.2]
MRCPICGGAELAPDVQGMPYSYKGEATVIPDVSGDYCSGCGECVLSHDEAMRVSNLMTAFERQVNATVVDPSFIASMRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT53136 NZ_CP010979:358643-359044 [Pseudomonas putida S13.1.2]
ATGAGATGTCCAATATGCGGCGGAGCGGAGCTTGCACCTGATGTTCAGGGCATGCCCTATAGCTATAAAGGCGAGGCGAC
CGTCATCCCTGACGTAAGTGGCGATTACTGTTCCGGATGTGGTGAATGTGTACTTAGCCACGATGAAGCCATGCGTGTCA
GTAACCTCATGACGGCATTCGAGCGCCAAGTCAACGCAACGGTTGTGGATCCTTCCTTCATTGCTTCAATGCGCCGGAAG
TTCGACCTCGACCAGCGTGAAGCGGGGGAAATCTTCGGTGGTGGGGTCAACGCGTTCTCCCGATATGAAAACGGCAAGAC
CACACCACCCGTGGCGTTGGTGAAACTGCTCAAGCTGCTGGATCGCCATCCAGAGCTCTTCGAGGAAGTGCGTACTGCCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5RRJ0

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5S3M0

References