53050

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2181777..2181993 Replicon chromosome
Accession NZ_CP010890
Organism Staphylococcus aureus strain SA564

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RT87_RS11035 Protein ID WP_001802298.1
Coordinates 2181889..2181993 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2181777..2181832 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RT87_RS11015 2177983..2178648 - 666 WP_001024095.1 SDR family oxidoreductase -
RT87_RS11020 2178800..2179120 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RT87_RS11025 2179122..2180099 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
RT87_RS11030 2180365..2181456 + 1092 WP_000495669.1 hypothetical protein -
- 2181777..2181832 + 56 - - Antitoxin
RT87_RS11035 2181889..2181993 - 105 WP_001802298.1 hypothetical protein Toxin
RT87_RS14660 2182673..2182831 + 159 WP_001792784.1 hypothetical protein -
RT87_RS11040 2183489..2184346 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
RT87_RS11045 2184414..2185196 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T53050 WP_001802298.1 NZ_CP010890:c2181993-2181889 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T53050 NZ_CP010890:c2181993-2181889 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT53050 NZ_CP010890:2181777-2181832 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References