Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2258315..2258577 Replicon chromosome
Accession NZ_CP010526
Organism Staphylococcus aureus subsp. aureus ST772-MRSA-V strain DAR4145

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RU53_RS15680 Protein ID WP_001802298.1
Coordinates 2258473..2258577 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2258315..2258478 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RU53_RS11405 2254567..2255232 - 666 WP_001024095.1 SDR family oxidoreductase -
RU53_RS11410 2255384..2255704 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RU53_RS11415 2255706..2256683 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
RU53_RS11420 2256949..2258040 + 1092 WP_000495669.1 hypothetical protein -
- 2258315..2258478 + 164 - - Antitoxin
RU53_RS15680 2258473..2258577 - 105 WP_001802298.1 hypothetical protein Toxin
RU53_RS15690 2259257..2259415 + 159 WP_001792784.1 hypothetical protein -
RU53_RS11430 2260073..2260930 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
RU53_RS11435 2260998..2261780 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T52781 WP_001802298.1 NZ_CP010526:c2258577-2258473 [Staphylococcus aureus subsp. aureus ST772-MRSA-V]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T52781 NZ_CP010526:c2258577-2258473 [Staphylococcus aureus subsp. aureus ST772-MRSA-V]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT52781 NZ_CP010526:2258315-2258478 [Staphylococcus aureus subsp. aureus ST772-MRSA-V]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References