Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1971611..1971791 Replicon chromosome
Accession NZ_CP010526
Organism Staphylococcus aureus subsp. aureus ST772-MRSA-V strain DAR4145

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag RU53_RS16195 Protein ID WP_001801861.1
Coordinates 1971611..1971706 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1971734..1971791 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RU53_RS09770 1967665..1968291 + 627 WP_000669025.1 hypothetical protein -
RU53_RS09775 1968318..1969061 + 744 WP_174840254.1 exotoxin -
RU53_RS09780 1969088..1969840 + 753 WP_000764922.1 staphylococcal enterotoxin type 27 -
RU53_RS09785 1969972..1970529 - 558 WP_000864141.1 ImmA/IrrE family metallo-endopeptidase -
RU53_RS09790 1970713..1971159 - 447 WP_000747808.1 DUF1433 domain-containing protein -
RU53_RS16195 1971611..1971706 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1971734..1971791 - 58 - - Antitoxin
RU53_RS09800 1972357..1974054 - 1698 WP_000447924.1 hypothetical protein -
RU53_RS09805 1974032..1974886 - 855 WP_001069960.1 DNA adenine methylase -
RU53_RS09810 1974925..1976190 - 1266 WP_000072555.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - selk 1965106..2002114 37008


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T52776 WP_001801861.1 NZ_CP010526:1971611-1971706 [Staphylococcus aureus subsp. aureus ST772-MRSA-V]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T52776 NZ_CP010526:1971611-1971706 [Staphylococcus aureus subsp. aureus ST772-MRSA-V]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT52776 NZ_CP010526:c1971791-1971734 [Staphylococcus aureus subsp. aureus ST772-MRSA-V]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References