52356

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2195744..2195961 Replicon chromosome
Accession NZ_CP010402
Organism Staphylococcus aureus strain GR2

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RT44_RS11135 Protein ID WP_001802298.1
Coordinates 2195857..2195961 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2195744..2195799 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RT44_RS11115 2191881..2192546 - 666 WP_001024094.1 SDR family oxidoreductase -
RT44_RS11120 2192698..2193018 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RT44_RS11125 2193020..2194000 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
RT44_RS11130 2194266..2195357 + 1092 WP_000495670.1 lytic regulatory protein -
- 2195744..2195799 + 56 - - Antitoxin
RT44_RS11135 2195857..2195961 - 105 WP_001802298.1 hypothetical protein Toxin
RT44_RS14835 2196641..2196799 + 159 WP_001792784.1 hypothetical protein -
RT44_RS11140 2197457..2198314 - 858 WP_000370929.1 Cof-type HAD-IIB family hydrolase -
RT44_RS11145 2198382..2199164 - 783 WP_000908179.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T52356 WP_001802298.1 NZ_CP010402:c2195961-2195857 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T52356 NZ_CP010402:c2195961-2195857 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT52356 NZ_CP010402:2195744-2195799 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References