Detailed information of TA system TA051992

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2049374..2049620
• Replicon: chromosome
• Accession: NZ_CP010314
• Organism: Bacillus subtilis subsp. subtilis strain 3NA isolate 1970 (Michel and Millet)

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: RP72_RS23605
• Protein ID: WP_109789044.1
• Coordinates: 2049374..2049466 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2049447..2049620 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RP72_RS10335	2044533..2044868	+	336	WP_009967409.1	hypothetical protein	-
RP72_RS10340	2044915..2048520	-	3606	WP_004399367.1	membrane protein	-
RP72_RS10345	2048753..2049085	-	333	WP_026009814.1	hypothetical protein	-
RP72_RS23605	2049374..2049466	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2049447..2049620	-	174	-	-	Antitoxin
RP72_RS10350	2049735..2050577	-	843	WP_003231327.1	hypothetical protein	-
RP72_RS10355	2050777..2051235	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
RP72_RS10360	2051245..2053047	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
RP72_RS10365	2053149..2053706	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2035359..2061238	25879

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T51992 WP_109789044.1 NZ_CP010314:2049374-2049466 [Bacillus subtilis subsp. subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T51992 NZ_CP010314:2049374-2049466 [Bacillus subtilis subsp. subtilis]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA

Antitoxin

Nucleotide

• Length: 174 bp

>AT51992 NZ_CP010314:c2049620-2049447 [Bacillus subtilis subsp. subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin