Detailed information of TA system TA051927

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2265133..2265350
• Replicon: chromosome
• Accession: NZ_CP010300
• Organism: Staphylococcus aureus strain ATCC BAA1680

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: RM28_RS14860
• Protein ID: WP_001802298.1
• Coordinates: 2265246..2265350 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF4
Locus tag	-
Coordinates	2265133..2265188 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RM28_RS10670	2261270..2261935	-	666	WP_001024094.1	SDR family oxidoreductase	-
RM28_RS10675	2262087..2262407	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
RM28_RS10680	2262409..2263389	+	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
RM28_RS10685	2263655..2264746	+	1092	WP_000495671.1	lytic regulatory protein	-
-	2265133..2265188	+	56	-	-	Antitoxin
RM28_RS14860	2265246..2265350	-	105	WP_001802298.1	hypothetical protein	Toxin
RM28_RS15430	2265511..2265994	-	484	Protein_2201	recombinase family protein	-
RM28_RS10695	2266037..2267173	-	1137	WP_000115564.1	SAP domain-containing protein	-
RM28_RS14865	2267462..2267554	+	93	WP_001790138.1	hypothetical protein	-
RM28_RS10700	2268259..2269116	-	858	WP_000370924.1	Cof-type HAD-IIB family hydrolase	-
RM28_RS10705	2269184..2269966	-	783	WP_000908176.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T51927 WP_001802298.1 NZ_CP010300:c2265350-2265246 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T51927 NZ_CP010300:c2265350-2265246 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT51927 NZ_CP010300:2265133-2265188 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin