Detailed information of TA system TA051911

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2265143..2265360
• Replicon: chromosome
• Accession: NZ_CP010299
• Organism: Staphylococcus aureus strain ATCC BAA1680

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: RM27_RS14870
• Protein ID: WP_001802298.1
• Coordinates: 2265256..2265360 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF4
Locus tag	-
Coordinates	2265143..2265198 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RM27_RS10675	2261280..2261945	-	666	WP_001024094.1	SDR family oxidoreductase	-
RM27_RS10680	2262097..2262417	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
RM27_RS10685	2262419..2263399	+	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
RM27_RS10690	2263665..2264756	+	1092	WP_000495671.1	lytic regulatory protein	-
-	2265143..2265198	+	56	-	-	Antitoxin
RM27_RS14870	2265256..2265360	-	105	WP_001802298.1	hypothetical protein	Toxin
RM27_RS15435	2265521..2266004	-	484	Protein_2202	recombinase family protein	-
RM27_RS10700	2266047..2267183	-	1137	WP_000115564.1	SAP domain-containing protein	-
RM27_RS14875	2267472..2267564	+	93	WP_001790138.1	hypothetical protein	-
RM27_RS10705	2268269..2269126	-	858	WP_000370924.1	Cof-type HAD-IIB family hydrolase	-
RM27_RS10710	2269194..2269976	-	783	WP_000908176.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T51911 WP_001802298.1 NZ_CP010299:c2265360-2265256 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T51911 NZ_CP010299:c2265360-2265256 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT51911 NZ_CP010299:2265143-2265198 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin