Detailed information of TA system TA051879

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2265124..2265341
• Replicon: chromosome
• Accession: NZ_CP010297
• Organism: Staphylococcus aureus strain ATCC BAA1680

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: QT38_RS14860
• Protein ID: WP_001802298.1
• Coordinates: 2265237..2265341 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF4
Locus tag	-
Coordinates	2265124..2265179 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QT38_RS10675	2261261..2261926	-	666	WP_001024094.1	SDR family oxidoreductase	-
QT38_RS10680	2262078..2262398	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
QT38_RS10685	2262400..2263380	+	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
QT38_RS10690	2263646..2264737	+	1092	WP_000495671.1	lytic regulatory protein	-
-	2265124..2265179	+	56	-	-	Antitoxin
QT38_RS14860	2265237..2265341	-	105	WP_001802298.1	hypothetical protein	Toxin
QT38_RS15425	2265502..2265985	-	484	Protein_2201	recombinase family protein	-
QT38_RS10700	2266028..2267164	-	1137	WP_000115564.1	SAP domain-containing protein	-
QT38_RS14865	2267453..2267545	+	93	WP_001790138.1	hypothetical protein	-
QT38_RS10705	2268250..2269107	-	858	WP_000370924.1	Cof-type HAD-IIB family hydrolase	-
QT38_RS10710	2269175..2269957	-	783	WP_000908176.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T51879 WP_001802298.1 NZ_CP010297:c2265341-2265237 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T51879 NZ_CP010297:c2265341-2265237 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT51879 NZ_CP010297:2265124-2265179 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin