51878

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2265078..2265341 Replicon chromosome
Accession NZ_CP010297
Organism Staphylococcus aureus strain ATCC BAA1680

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag QT38_RS14860 Protein ID WP_001802298.1
Coordinates 2265237..2265341 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2265078..2265242 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QT38_RS10675 2261261..2261926 - 666 WP_001024094.1 SDR family oxidoreductase -
QT38_RS10680 2262078..2262398 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
QT38_RS10685 2262400..2263380 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
QT38_RS10690 2263646..2264737 + 1092 WP_000495671.1 lytic regulatory protein -
- 2265078..2265242 + 165 - - Antitoxin
QT38_RS14860 2265237..2265341 - 105 WP_001802298.1 hypothetical protein Toxin
QT38_RS15425 2265502..2265985 - 484 Protein_2201 recombinase family protein -
QT38_RS10700 2266028..2267164 - 1137 WP_000115564.1 SAP domain-containing protein -
QT38_RS14865 2267453..2267545 + 93 WP_001790138.1 hypothetical protein -
QT38_RS10705 2268250..2269107 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
QT38_RS10710 2269175..2269957 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T51878 WP_001802298.1 NZ_CP010297:c2265341-2265237 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T51878 NZ_CP010297:c2265341-2265237 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT51878 NZ_CP010297:2265078-2265242 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References