51865

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2555439..2555623 Replicon chromosome
Accession NZ_CP010296
Organism Staphylococcus aureus strain ATCC BAA1680

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag RM30_RS15060 Protein ID WP_000482650.1
Coordinates 2555516..2555623 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2555439..2555499 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RM30_RS15040 2550969..2551136 - 168 WP_001790576.1 hypothetical protein -
RM30_RS12085 2551367..2553100 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
RM30_RS12090 2553125..2554888 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2555439..2555499 + 61 - - Antitoxin
RM30_RS15060 2555516..2555623 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
RM30_RS12095 2555757..2556143 - 387 WP_000779358.1 flippase GtxA -
RM30_RS12100 2556411..2557553 + 1143 WP_001176863.1 glycerate kinase -
RM30_RS12105 2557613..2558272 + 660 WP_000831298.1 membrane protein -
RM30_RS12110 2558454..2559665 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
RM30_RS12115 2559788..2560261 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T51865 WP_000482650.1 NZ_CP010296:c2555623-2555516 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T51865 NZ_CP010296:c2555623-2555516 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT51865 NZ_CP010296:2555439-2555499 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References