Detailed information of TA system TA051863

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2265139..2265356
• Replicon: chromosome
• Accession: NZ_CP010296
• Organism: Staphylococcus aureus strain ATCC BAA1680

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: RM30_RS14860
• Protein ID: WP_001802298.1
• Coordinates: 2265252..2265356 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF4
Locus tag	-
Coordinates	2265139..2265194 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RM30_RS10670	2261276..2261941	-	666	WP_001024094.1	SDR family oxidoreductase	-
RM30_RS10675	2262093..2262413	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
RM30_RS10680	2262415..2263395	+	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
RM30_RS10685	2263661..2264752	+	1092	WP_000495671.1	lytic regulatory protein	-
-	2265139..2265194	+	56	-	-	Antitoxin
RM30_RS14860	2265252..2265356	-	105	WP_001802298.1	hypothetical protein	Toxin
RM30_RS15425	2265517..2266000	-	484	Protein_2202	recombinase family protein	-
RM30_RS10695	2266043..2267179	-	1137	WP_000115564.1	SAP domain-containing protein	-
RM30_RS14865	2267468..2267560	+	93	WP_001790138.1	hypothetical protein	-
RM30_RS10700	2268265..2269122	-	858	WP_000370924.1	Cof-type HAD-IIB family hydrolase	-
RM30_RS10705	2269190..2269972	-	783	WP_000908176.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T51863 WP_001802298.1 NZ_CP010296:c2265356-2265252 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T51863 NZ_CP010296:c2265356-2265252 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT51863 NZ_CP010296:2265139-2265194 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin