51862

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2265093..2265356 Replicon chromosome
Accession NZ_CP010296
Organism Staphylococcus aureus strain ATCC BAA1680

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag RM30_RS14860 Protein ID WP_001802298.1
Coordinates 2265252..2265356 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2265093..2265257 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RM30_RS10670 2261276..2261941 - 666 WP_001024094.1 SDR family oxidoreductase -
RM30_RS10675 2262093..2262413 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
RM30_RS10680 2262415..2263395 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
RM30_RS10685 2263661..2264752 + 1092 WP_000495671.1 lytic regulatory protein -
- 2265093..2265257 + 165 - - Antitoxin
RM30_RS14860 2265252..2265356 - 105 WP_001802298.1 hypothetical protein Toxin
RM30_RS15425 2265517..2266000 - 484 Protein_2202 recombinase family protein -
RM30_RS10695 2266043..2267179 - 1137 WP_000115564.1 SAP domain-containing protein -
RM30_RS14865 2267468..2267560 + 93 WP_001790138.1 hypothetical protein -
RM30_RS10700 2268265..2269122 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
RM30_RS10705 2269190..2269972 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T51862 WP_001802298.1 NZ_CP010296:c2265356-2265252 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T51862 NZ_CP010296:c2265356-2265252 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT51862 NZ_CP010296:2265093-2265257 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References