Detailed information of TA system TA051837

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1929116..1929298
• Replicon: chromosome
• Accession: NZ_CP010295
• Organism: Staphylococcus aureus strain ATCC BAA1680

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: RM29_RS15400
• Protein ID: WP_144245636.1
• Coordinates: 1929116..1929211 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1929239..1929298 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RM29_RS15545	1924362..1924700	+	339	WP_173401752.1	hypothetical protein	-
RM29_RS08835	1924776..1925402	+	627	Protein_1841	hypothetical protein	-
RM29_RS08840	1925443..1925787	+	345	WP_000627551.1	DUF3969 family protein	-
RM29_RS08845	1925885..1926436	+	552	WP_000414205.1	hypothetical protein	-
RM29_RS08850	1926654..1927295	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
RM29_RS08855	1927409..1927594	-	186	WP_000809857.1	hypothetical protein	-
RM29_RS14550	1927596..1927772	-	177	WP_000375476.1	hypothetical protein	-
RM29_RS08865	1927783..1928166	-	384	WP_000070811.1	hypothetical protein	-
RM29_RS14560	1928770..1928913	-	144	WP_001549059.1	transposase	-
RM29_RS15400	1929116..1929211	+	96	WP_144245636.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1929239..1929298	-	60	-	-	Antitoxin
RM29_RS14565	1929334..1929435	+	102	WP_001791893.1	hypothetical protein	-
RM29_RS14570	1929413..1929589	-	177	Protein_1851	transposase	-
RM29_RS08875	1929783..1930160	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1922215..1947818	25603

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T51837 WP_144245636.1 NZ_CP010295:1929116-1929211 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T51837 NZ_CP010295:1929116-1929211 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT51837 NZ_CP010295:c1929298-1929239 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin