Detailed information of TA system TA051734

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ralRA/-
• Location: 3339644..3340015
• Replicon: chromosome
• Accession: NZ_CP010240
• Organism: Escherichia coli strain C7

Toxin (Protein)

• Gene name: ralR
• Uniprot ID: A0A839BBC2
• Locus tag: RG29_RS17665
• Protein ID: WP_021500490.1
• Coordinates: 3339821..3340015 (-)
• Length: 65 a.a.

Antitoxin (RNA)

Gene name	ralA
Locus tag	-
Coordinates	3339644..3339822 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RG29_RS17640	3335599..3336972	+	1374	WP_000123745.1	ATP-dependent RNA helicase DbpA	-
RG29_RS17645	3337101..3338036	-	936	WP_001157394.1	tRNA 2-thiocytidine(32) synthetase TtcA	-
RG29_RS17650	3338088..3339323	-	1236	WP_000040844.1	site-specific integrase	-
RG29_RS17655	3339325..3339540	-	216	WP_000079604.1	excisionase XisR	-
RG29_RS17660	3339640..3339828	-	189	WP_073519364.1	DUF1187 family protein	-
-	3339644..3339822	+	179	NuclAT_0	-	Antitoxin
-	3339644..3339822	+	179	NuclAT_0	-	Antitoxin
-	3339644..3339822	+	179	NuclAT_0	-	Antitoxin
-	3339644..3339822	+	179	NuclAT_0	-	Antitoxin
RG29_RS17665	3339821..3340015	-	195	WP_021500490.1	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	Toxin
RG29_RS17670	3340079..3341167	-	1089	WP_063100796.1	recombinase RecT	-
RG29_RS17675	3341182..3344343	-	3162	WP_073519365.1	exodeoxyribonuclease VIII	-
RG29_RS17680	3344444..3344719	-	276	WP_073519366.1	hypothetical protein	-
RG29_RS17685	3344794..3344970	-	177	WP_000245533.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	3338088..3386819	48731

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Endodeoxyribonuclease toxin RalR (6-54)

Sequences

Toxin

Protein

• Length: 65 a.a.
• Molecular weight: 7046.98 Da
• Isoelectric Point: 9.2886

>T51734 WP_021500490.1 NZ_CP010240:c3340015-3339821 [Escherichia coli]
MRYEKVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV

Nucleotide

• Length: 195 bp

>T51734 NZ_CP010240:c3340015-3339821 [Escherichia coli]
ATGCGGTATGAAAAAGTCAAACCATGTCCGTTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
CGCAAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CCACTGGAAATAATAATGGAGGTGTTCATGTATAA

Antitoxin

Nucleotide

• Length: 179 bp

>AT51734 NZ_CP010240:3339644-3339822 [Escherichia coli]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTCCCTGA
GAGCATTTTTTCGCATTCCGATTTGGTTAACTTTGTTTTTGAGTACCTTGTCCAGCTGGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT

Structures

Toxin

• AlphaFold DB: A0A839BBC2

Antitoxin