Detailed information of TA system TA051637

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ralRA/-
• Location: 1238056..1238427
• Replicon: chromosome
• Accession: NZ_CP010236
• Organism: Escherichia coli strain S42

Toxin (Protein)

• Gene name: ralR
• Uniprot ID: -
• Locus tag: RG70_RS06540
• Protein ID: WP_053889809.1
• Coordinates: 1238233..1238427 (-)
• Length: 65 a.a.

Antitoxin (RNA)

Gene name	ralA
Locus tag	-
Coordinates	1238056..1238234 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RG70_RS06515	1234011..1235384	+	1374	WP_000123738.1	ATP-dependent RNA helicase DbpA	-
RG70_RS06520	1235513..1236448	-	936	WP_001157407.1	tRNA 2-thiocytidine(32) synthetase TtcA	-
RG70_RS06525	1236500..1237735	-	1236	WP_000040852.1	site-specific integrase	-
RG70_RS06530	1237737..1237952	-	216	WP_000079604.1	excisionase XisR	-
RG70_RS06535	1238031..1238240	-	210	WP_000276809.1	double-strand break reduction protein RcbA	-
-	1238056..1238234	+	179	NuclAT_0	-	Antitoxin
-	1238056..1238234	+	179	NuclAT_0	-	Antitoxin
-	1238056..1238234	+	179	NuclAT_0	-	Antitoxin
-	1238056..1238234	+	179	NuclAT_0	-	Antitoxin
RG70_RS06540	1238233..1238427	-	195	WP_053889809.1	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	Toxin
RG70_RS06545	1238484..1239293	-	810	WP_000166319.1	recombination protein RecT	-
RG70_RS06550	1239286..1241886	-	2601	WP_073520447.1	exodeoxyribonuclease VIII	-
RG70_RS06555	1241988..1242263	-	276	WP_000632297.1	protein RacC	-
RG70_RS06560	1242338..1242508	-	171	WP_001352098.1	conserved protein, Rac prophage	-
RG70_RS06565	1242508..1242729	-	222	WP_000560223.1	killing protein KilR	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1236500..1285051	48551

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Endodeoxyribonuclease toxin RalR (6-54)

Sequences

Toxin

Protein

• Length: 65 a.a.
• Molecular weight: 7032.91 Da
• Isoelectric Point: 8.9538

>T51637 WP_053889809.1 NZ_CP010236:c1238427-1238233 [Escherichia coli]
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGIHV

Nucleotide

• Length: 195 bp

>T51637 NZ_CP010236:c1238427-1238233 [Escherichia coli]
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CCACTGGAAATAATAATGGAGGTATTCATGTATAA

Antitoxin

Nucleotide

• Length: 179 bp

>AT51637 NZ_CP010236:1238056-1238234 [Escherichia coli]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT

Structures

Antitoxin