Detailed information of TA system TA051366

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ralRA/-
• Location: 1382792..1383163
• Replicon: chromosome
• Accession: NZ_CP010206
• Organism: Escherichia coli strain M11

Toxin (Protein)

• Gene name: ralR
• Uniprot ID: A0A891STD1
• Locus tag: RG60_RS07065
• Protein ID: WP_042853000.1
• Coordinates: 1382969..1383163 (-)
• Length: 65 a.a.

Antitoxin (RNA)

Gene name	ralA
Locus tag	-
Coordinates	1382792..1382970 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RG60_RS07020	1378234..1378890	-	657	WP_000011652.1	carbon-nitrogen hydrolase family protein	-
RG60_RS07025	1378992..1379222	-	231	WP_000916763.1	DNA polymerase III subunit theta	-
RG60_RS07030	1379361..1379735	+	375	WP_000204699.1	CopC domain-containing protein YobA	-
RG60_RS07035	1379739..1380611	+	873	WP_000879280.1	copper homeostasis membrane protein CopD	-
RG60_RS07040	1380624..1380965	+	342	WP_000976492.1	YebY family protein	-
RG60_RS07050	1381358..1382434	-	1077	WP_001189091.1	phage integrase Arm DNA-binding domain-containing protein	-
RG60_RS07055	1382400..1382681	-	282	WP_001311878.1	excisionase	-
RG60_RS07060	1382788..1382976	-	189	WP_001356607.1	DUF1187 family protein	-
-	1382792..1382970	+	179	NuclAT_0	-	Antitoxin
-	1382792..1382970	+	179	NuclAT_0	-	Antitoxin
-	1382792..1382970	+	179	NuclAT_0	-	Antitoxin
-	1382792..1382970	+	179	NuclAT_0	-	Antitoxin
RG60_RS07065	1382969..1383163	-	195	WP_042853000.1	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	Toxin
RG60_RS07070	1383220..1384029	-	810	WP_000166317.1	recombination protein RecT	-
RG60_RS07075	1384022..1386655	-	2634	WP_021527613.1	exodeoxyribonuclease VIII	-
RG60_RS07080	1386754..1387029	-	276	WP_001452559.1	hypothetical protein	-
RG60_RS07085	1387104..1387274	-	171	WP_001359121.1	hypothetical protein	-
RG60_RS07090	1387274..1387495	-	222	WP_073519610.1	cell division protein FtsZ	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1377548..1439419	61871

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Endodeoxyribonuclease toxin RalR (6-54)

Sequences

Toxin

Protein

• Length: 65 a.a.
• Molecular weight: 7019.87 Da
• Isoelectric Point: 8.6419

>T51366 WP_042853000.1 NZ_CP010206:c1383163-1382969 [Escherichia coli]
MRYDDVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV

Nucleotide

• Length: 195 bp

>T51366 NZ_CP010206:c1383163-1382969 [Escherichia coli]
ATGAGATATGACGATGTTAAACCATGTCCGTTTTGTGGTTGTCCATCTGTTACGGTGAAAGCAATTTCAGGATATTACCG
GGCAAAATGCAACGGATGCGAATCCCGAACTGGCTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CTACTGGAAATAATAATGGAGGTGTTCATGTATAA

Antitoxin

Nucleotide

• Length: 179 bp

>AT51366 NZ_CP010206:1382792-1382970 [Escherichia coli]
GAGGACAGAAGTTTCTCGCAATTAAAATTTATCAGCTTTACTTTCTGCTCTCTGGACACGCCTGCTTCTTTTTTCCCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAATTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCTTTTT
CAATAGTGGCAGTTATTTT

Structures

Antitoxin