Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | ldrD-rdlD/Ldr(toxin) |
Location | 37850..38070 | Replicon | chromosome |
Accession | NZ_CP010180 | ||
Organism | Escherichia coli strain M1 |
Toxin (Protein)
Gene name | ldrD | Uniprot ID | S1PGT3 |
Locus tag | RG54_RS00185 | Protein ID | WP_000170954.1 |
Coordinates | 37850..37957 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | rdlD | ||
Locus tag | - | ||
Coordinates | 38007..38070 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
RG54_RS00160 | 33694..34776 | + | 1083 | WP_000804726.1 | peptide chain release factor 1 | - |
RG54_RS00165 | 34776..35609 | + | 834 | WP_000456571.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
RG54_RS00170 | 35606..35998 | + | 393 | WP_032283162.1 | invasion regulator SirB2 | - |
RG54_RS00175 | 36002..36811 | + | 810 | WP_001257044.1 | invasion regulator SirB1 | - |
RG54_RS00180 | 36847..37701 | + | 855 | WP_000811065.1 | 3-deoxy-8-phosphooctulonate synthase | - |
RG54_RS00185 | 37850..37957 | - | 108 | WP_000170954.1 | type I toxin-antitoxin system toxin Ldr family protein | Toxin |
- | 38007..38070 | + | 64 | NuclAT_46 | - | Antitoxin |
- | 38007..38070 | + | 64 | NuclAT_46 | - | Antitoxin |
- | 38007..38070 | + | 64 | NuclAT_46 | - | Antitoxin |
- | 38007..38070 | + | 64 | NuclAT_46 | - | Antitoxin |
- | 38007..38070 | + | 64 | NuclAT_49 | - | Antitoxin |
- | 38007..38070 | + | 64 | NuclAT_49 | - | Antitoxin |
- | 38007..38070 | + | 64 | NuclAT_49 | - | Antitoxin |
- | 38007..38070 | + | 64 | NuclAT_49 | - | Antitoxin |
RG54_RS27675 | 38385..38492 | - | 108 | WP_000170926.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
- | 38545..38606 | + | 62 | NuclAT_45 | - | - |
- | 38545..38606 | + | 62 | NuclAT_45 | - | - |
- | 38545..38606 | + | 62 | NuclAT_45 | - | - |
- | 38545..38606 | + | 62 | NuclAT_45 | - | - |
- | 38545..38606 | + | 62 | NuclAT_48 | - | - |
- | 38545..38606 | + | 62 | NuclAT_48 | - | - |
- | 38545..38606 | + | 62 | NuclAT_48 | - | - |
- | 38545..38606 | + | 62 | NuclAT_48 | - | - |
- | 38545..38608 | + | 64 | NuclAT_15 | - | - |
- | 38545..38608 | + | 64 | NuclAT_15 | - | - |
- | 38545..38608 | + | 64 | NuclAT_15 | - | - |
- | 38545..38608 | + | 64 | NuclAT_15 | - | - |
- | 38545..38608 | + | 64 | NuclAT_17 | - | - |
- | 38545..38608 | + | 64 | NuclAT_17 | - | - |
- | 38545..38608 | + | 64 | NuclAT_17 | - | - |
- | 38545..38608 | + | 64 | NuclAT_17 | - | - |
- | 38545..38608 | + | 64 | NuclAT_19 | - | - |
- | 38545..38608 | + | 64 | NuclAT_19 | - | - |
- | 38545..38608 | + | 64 | NuclAT_19 | - | - |
- | 38545..38608 | + | 64 | NuclAT_19 | - | - |
- | 38545..38608 | + | 64 | NuclAT_21 | - | - |
- | 38545..38608 | + | 64 | NuclAT_21 | - | - |
- | 38545..38608 | + | 64 | NuclAT_21 | - | - |
- | 38545..38608 | + | 64 | NuclAT_21 | - | - |
- | 38545..38608 | + | 64 | NuclAT_23 | - | - |
- | 38545..38608 | + | 64 | NuclAT_23 | - | - |
- | 38545..38608 | + | 64 | NuclAT_23 | - | - |
- | 38545..38608 | + | 64 | NuclAT_23 | - | - |
- | 38545..38608 | + | 64 | NuclAT_25 | - | - |
- | 38545..38608 | + | 64 | NuclAT_25 | - | - |
- | 38545..38608 | + | 64 | NuclAT_25 | - | - |
- | 38545..38608 | + | 64 | NuclAT_25 | - | - |
RG54_RS00205 | 38921..39028 | - | 108 | WP_000170965.1 | type I toxin-antitoxin system toxin Ldr family protein | - |
- | 39076..39141 | + | 66 | NuclAT_44 | - | - |
- | 39076..39141 | + | 66 | NuclAT_44 | - | - |
- | 39076..39141 | + | 66 | NuclAT_44 | - | - |
- | 39076..39141 | + | 66 | NuclAT_44 | - | - |
- | 39076..39141 | + | 66 | NuclAT_47 | - | - |
- | 39076..39141 | + | 66 | NuclAT_47 | - | - |
- | 39076..39141 | + | 66 | NuclAT_47 | - | - |
- | 39076..39141 | + | 66 | NuclAT_47 | - | - |
- | 39076..39143 | + | 68 | NuclAT_14 | - | - |
- | 39076..39143 | + | 68 | NuclAT_14 | - | - |
- | 39076..39143 | + | 68 | NuclAT_14 | - | - |
- | 39076..39143 | + | 68 | NuclAT_14 | - | - |
- | 39076..39143 | + | 68 | NuclAT_16 | - | - |
- | 39076..39143 | + | 68 | NuclAT_16 | - | - |
- | 39076..39143 | + | 68 | NuclAT_16 | - | - |
- | 39076..39143 | + | 68 | NuclAT_16 | - | - |
- | 39076..39143 | + | 68 | NuclAT_18 | - | - |
- | 39076..39143 | + | 68 | NuclAT_18 | - | - |
- | 39076..39143 | + | 68 | NuclAT_18 | - | - |
- | 39076..39143 | + | 68 | NuclAT_18 | - | - |
- | 39076..39143 | + | 68 | NuclAT_20 | - | - |
- | 39076..39143 | + | 68 | NuclAT_20 | - | - |
- | 39076..39143 | + | 68 | NuclAT_20 | - | - |
- | 39076..39143 | + | 68 | NuclAT_20 | - | - |
- | 39076..39143 | + | 68 | NuclAT_22 | - | - |
- | 39076..39143 | + | 68 | NuclAT_22 | - | - |
- | 39076..39143 | + | 68 | NuclAT_22 | - | - |
- | 39076..39143 | + | 68 | NuclAT_22 | - | - |
- | 39076..39143 | + | 68 | NuclAT_24 | - | - |
- | 39076..39143 | + | 68 | NuclAT_24 | - | - |
- | 39076..39143 | + | 68 | NuclAT_24 | - | - |
- | 39076..39143 | + | 68 | NuclAT_24 | - | - |
RG54_RS00215 | 39433..40533 | - | 1101 | WP_001295620.1 | sodium-potassium/proton antiporter ChaA | - |
RG54_RS00220 | 40803..41033 | + | 231 | WP_001146442.1 | putative cation transport regulator ChaB | - |
RG54_RS00225 | 41191..41886 | + | 696 | WP_001297117.1 | glutathione-specific gamma-glutamylcyclotransferase | - |
RG54_RS00230 | 41930..42283 | - | 354 | WP_001169669.1 | DsrE/F sulfur relay family protein YchN | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 3983.80 Da Isoelectric Point: 11.4779
>T51181 WP_000170954.1 NZ_CP010180:c37957-37850 [Escherichia coli]
MTLAQFAMIFWHDLAAPILAGIITAAIVGWWRNRK
MTLAQFAMIFWHDLAAPILAGIITAAIVGWWRNRK
Download Length: 108 bp
>T51181 NZ_CP010180:c37957-37850 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 64 bp
>AT51181 NZ_CP010180:38007-38070 [Escherichia coli]
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTAAAACCTCTCAACGTGCGGGGGTTTTCT
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTAAAACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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