Detailed information of TA system TA050911

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 205895..206117
• Replicon: chromosome
• Accession: NZ_CP010157
• Organism: Escherichia coli strain D10

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: RG43_RS28770
• Protein ID: WP_001295224.1
• Coordinates: 206010..206117 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	205895..205953 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RG43_RS01075	201780..202784	+	1005	WP_000107036.1	dipeptide ABC transporter ATP-binding subunit DppF	-
RG43_RS01080	202814..204085	-	1272	WP_001318103.1	amino acid permease	-
RG43_RS28755	204561..204668	+	108	WP_000170738.1	type I toxin-antitoxin system toxin Ldr family protein	-
RG43_RS01100	205044..205151	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
RG43_RS28760	205527..205634	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
-	205895..205953	-	59	-	-	Antitoxin
RG43_RS28770	206010..206117	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
RG43_RS01120	206204..207883	-	1680	WP_001562264.1	cellulose biosynthesis protein BcsG	-
RG43_RS01125	207880..208071	-	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
RG43_RS01130	208068..209639	-	1572	WP_001204944.1	cellulose biosynthesis protein BcsE	-
RG43_RS01135	209912..210100	+	189	WP_001063315.1	YhjR family protein	-
RG43_RS01145	210112..210864	+	753	Protein_196	cellulose biosynthesis protein BcsQ	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T50911 WP_001295224.1 NZ_CP010157:206010-206117 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

>T50911 NZ_CP010157:206010-206117 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 59 bp

>AT50911 NZ_CP010157:c205953-205895 [Escherichia coli]
TCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin