Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 204446..204668 Replicon chromosome
Accession NZ_CP010157
Organism Escherichia coli strain D10

Toxin (Protein)


Gene name ldrD Uniprot ID A0A829L523
Locus tag RG43_RS28755 Protein ID WP_000170738.1
Coordinates 204561..204668 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 204446..204512 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG43_RS01065 199887..200789 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
RG43_RS01070 200800..201783 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
RG43_RS01075 201780..202784 + 1005 WP_000107036.1 dipeptide ABC transporter ATP-binding subunit DppF -
RG43_RS01080 202814..204085 - 1272 WP_001318103.1 amino acid permease -
- 204446..204512 - 67 - - Antitoxin
RG43_RS28755 204561..204668 + 108 WP_000170738.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
RG43_RS01100 205044..205151 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
RG43_RS28760 205527..205634 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
RG43_RS28770 206010..206117 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
RG43_RS01120 206204..207883 - 1680 WP_001562264.1 cellulose biosynthesis protein BcsG -
RG43_RS01125 207880..208071 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
RG43_RS01130 208068..209639 - 1572 WP_001204944.1 cellulose biosynthesis protein BcsE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3864.67 Da        Isoelectric Point: 9.0157

>T50909 WP_000170738.1 NZ_CP010157:204561-204668 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASLIVNWLNKRK

Download         Length: 108 bp

>T50909 NZ_CP010157:204561-204668 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATAGCTGGCATTCTTGCCAGTCTGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT50909 NZ_CP010157:c204512-204446 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A829L523

Antitoxin

Download structure file

References