Detailed information of TA system TA050244

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2283846..2284171
• Replicon: chromosome
• Accession: NZ_CP010014
• Organism: Bacillus sp. YP1

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: P54373
• Locus tag: QF06_RS11205
• Protein ID: WP_004398662.1
• Coordinates: 2283846..2284025 (+)
• Length: 60 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2283949..2284171 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QF06_RS21270	2283072..2283209	-	138	WP_021480099.1	hypothetical protein	-
QF06_RS11200	2283251..2283700	-	450	WP_032722171.1	phage portal protein	-
QF06_RS11205	2283846..2284025	+	180	WP_004398662.1	type I toxin-antitoxin system toxin TxpA	Toxin
-	2283949..2284171	-	223	NuclAT_0	-	Antitoxin
-	2283949..2284171	-	223	NuclAT_0	-	Antitoxin
-	2283949..2284171	-	223	NuclAT_0	-	Antitoxin
-	2283949..2284171	-	223	NuclAT_0	-	Antitoxin
QF06_RS21825	2284405..2284494	+	90	WP_075058862.1	type I toxin-antitoxin system toxin BsrH	-
QF06_RS11210	2284748..2285191	-	444	WP_003229930.1	phage tail tube protein	-
QF06_RS11215	2285194..2286594	-	1401	WP_003229929.1	phage tail sheath family protein	-
QF06_RS11220	2286595..2286786	-	192	WP_010886574.1	hypothetical protein	-
QF06_RS11225	2286783..2287220	-	438	WP_003229927.1	hypothetical protein	-
QF06_RS11230	2287233..2287736	-	504	WP_003246050.1	HK97 gp10 family phage protein	-
QF06_RS11235	2287733..2288095	-	363	WP_003229925.1	YqbH/XkdH family protein	-
QF06_RS11240	2288092..2288487	-	396	WP_004398566.1	DUF3199 family protein	-
QF06_RS11245	2288491..2288802	-	312	WP_003229923.1	YqbF domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2253355..2304849	51494

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6739.19 Da
• Isoelectric Point: 8.0370

>T50244 WP_004398662.1 NZ_CP010014:2283846-2284025 [Bacillus sp. YP1]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Nucleotide

• Length: 180 bp

>T50244 NZ_CP010014:2283846-2284025 [Bacillus sp. YP1]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin

Nucleotide

• Length: 223 bp

>AT50244 NZ_CP010014:c2284171-2283949 [Bacillus sp. YP1]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Structures

Toxin

• AlphaFold DB: A0A164X333

Antitoxin