Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1430467..1430969 Replicon chromosome
Accession NZ_CP009838
Organism Yersinia enterocolitica strain 2516-87

Toxin (Protein)


Gene name yoeB Uniprot ID A0A7T9Y4I7
Locus tag CH48_RS06675 Protein ID WP_005156563.1
Coordinates 1430467..1430721 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7U7FIK7
Locus tag CH48_RS06680 Protein ID WP_005156566.1
Coordinates 1430718..1430969 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CH48_RS06665 1425556..1427688 - 2133 WP_013649108.1 TonB-dependent siderophore receptor -
CH48_RS06670 1428107..1430443 + 2337 WP_005156561.1 mechanosensitive ion channel family protein -
CH48_RS06675 1430467..1430721 - 255 WP_005156563.1 Txe/YoeB family addiction module toxin Toxin
CH48_RS06680 1430718..1430969 - 252 WP_005156566.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
CH48_RS06685 1431100..1433886 - 2787 WP_013649106.1 insulinase family protein -
CH48_RS06690 1433871..1435616 - 1746 WP_013649105.1 ABC transporter ATP-binding protein/permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10097.60 Da        Isoelectric Point: 9.4486

>T49930 WP_005156563.1 NZ_CP009838:c1430721-1430467 [Yersinia enterocolitica]
VRIIFSSCSWEDYLYWQQTDKKILKRINELVKNIQRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYEVSGDNLLIAAC
RYHY

Download         Length: 255 bp

>T49930 NZ_CP009838:c1430721-1430467 [Yersinia enterocolitica]
GTGAGAATTATATTTTCCAGTTGTTCTTGGGAGGATTATCTTTATTGGCAACAAACGGATAAGAAAATCCTCAAACGCAT
TAATGAGTTAGTAAAAAATATTCAAAGAACGCCATTTGAGGGAAAGGGTAAACCGGAACCCCTTAAACATAATCTGGCAG
GGTTCTGGTCACGGAGGATTACAGAAGAGCACAGACTTGTTTATGAGGTTTCCGGTGATAATTTATTAATTGCTGCTTGT
CGTTACCATTATTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9447.66 Da        Isoelectric Point: 4.4878

>AT49930 WP_005156566.1 NZ_CP009838:c1430969-1430718 [Yersinia enterocolitica]
MRTISYSEARQNLSTTMVQTVEDRAPILITRQNGTSCVLMSLEEYESLEETAYLLRSPANAKHLMDSIEELRAGKGIQRE
LEE

Download         Length: 252 bp

>AT49930 NZ_CP009838:c1430969-1430718 [Yersinia enterocolitica]
ATGAGAACAATTAGTTATAGTGAGGCGCGCCAGAATTTGTCGACAACGATGGTGCAAACGGTTGAGGATCGAGCCCCCAT
CCTCATCACTCGTCAAAATGGGACTTCTTGTGTTCTTATGTCACTTGAAGAATATGAATCATTGGAAGAAACTGCTTATT
TACTGCGCTCACCAGCAAACGCGAAGCATTTGATGGACTCAATTGAAGAGTTGAGAGCAGGAAAAGGAATTCAAAGGGAA
CTTGAAGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7T9Y4I7

Antitoxin

Source ID Structure
AlphaFold DB A0A7U7FIK7

References