Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 902793..903487 Replicon chromosome
Accession NZ_CP009838
Organism Yersinia enterocolitica strain 2516-87

Toxin (Protein)


Gene name mqsR Uniprot ID A0A7U7FJ92
Locus tag CH48_RS04440 Protein ID WP_005166025.1
Coordinates 903191..903487 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A7U7IQA2
Locus tag CH48_RS04435 Protein ID WP_005166024.1
Coordinates 902793..903191 (-) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CH48_RS04410 898193..899437 - 1245 WP_005166619.1 sensor domain-containing diguanylate cyclase -
CH48_RS04415 899520..899915 - 396 WP_005166615.1 SgcJ/EcaC family oxidoreductase -
CH48_RS04420 900287..901123 - 837 Protein_767 Fic family protein -
CH48_RS04425 901141..901341 + 201 WP_005166614.1 AlpA family transcriptional regulator -
CH48_RS04430 901484..902686 + 1203 WP_013649347.1 IS256 family transposase -
CH48_RS04435 902793..903191 - 399 WP_005166024.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
CH48_RS04440 903191..903487 - 297 WP_005166025.1 type II toxin-antitoxin system MqsR family toxin Toxin
CH48_RS04445 903644..904006 - 363 WP_005166026.1 helix-turn-helix domain-containing protein -
CH48_RS04450 904072..904332 - 261 WP_005166028.1 type II toxin-antitoxin system RelE/ParE family toxin -
CH48_RS04455 905546..906010 - 465 WP_032904770.1 helix-turn-helix domain-containing protein -
CH48_RS04460 906250..906744 + 495 WP_032904342.1 hypothetical protein -
CH48_RS04465 906787..907956 - 1170 WP_032904343.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(75-128)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11322.18 Da        Isoelectric Point: 7.7766

>T49926 WP_005166025.1 NZ_CP009838:c903487-903191 [Yersinia enterocolitica]
MEKRTPHTRLLKVKELVLKGNVKSTRTARDGAEELGLSFRDMCDVVCELTSADFYKSMTTHQDHTIWQDVYRPMLSCGRV
YLKITVIDDVLIVSFKEL

Download         Length: 297 bp

>T49926 NZ_CP009838:c903487-903191 [Yersinia enterocolitica]
ATGGAGAAACGGACTCCGCATACTCGTTTACTAAAAGTAAAAGAATTGGTATTGAAAGGGAATGTTAAATCGACTCGAAC
TGCCAGAGATGGCGCTGAAGAGCTGGGGCTGAGTTTTAGGGATATGTGTGATGTAGTTTGCGAACTGACTAGCGCCGATT
TTTATAAAAGTATGACGACACATCAAGATCATACGATTTGGCAGGATGTTTACCGCCCCATGCTTTCGTGCGGTAGAGTT
TATTTGAAAATCACGGTTATCGATGATGTTTTGATTGTCTCGTTTAAGGAGCTTTAA

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14716.19 Da        Isoelectric Point: 8.8165

>AT49926 WP_005166024.1 NZ_CP009838:c903191-902793 [Yersinia enterocolitica]
MMKCPVCGGAELIHEARDVPFTYKGRKFIVEGVIGQHCPACGETIMTEAESDTYAAKTMLLRKMVNTESIAPAYIVQVRK
KLGLNQREASEIFGGGVNAFSRYEKGKALPHRSTIKLLQVLDKYPELLNEIR

Download         Length: 399 bp

>AT49926 NZ_CP009838:c903191-902793 [Yersinia enterocolitica]
ATGATGAAATGCCCAGTTTGTGGTGGTGCAGAATTAATCCACGAAGCGCGTGACGTCCCCTTTACCTATAAAGGGCGTAA
GTTCATCGTCGAAGGCGTGATAGGACAACATTGCCCGGCATGCGGTGAAACAATCATGACTGAAGCTGAGTCCGATACCT
ATGCCGCAAAAACAATGCTTTTGCGAAAAATGGTTAATACAGAATCGATTGCACCCGCATATATTGTGCAGGTGCGAAAA
AAATTGGGTCTAAACCAGCGGGAAGCTAGTGAGATTTTTGGCGGTGGAGTGAATGCTTTTTCGCGTTACGAAAAGGGTAA
GGCGTTGCCACACCGTTCAACGATAAAATTGTTGCAAGTGCTTGATAAATATCCTGAGTTATTGAATGAAATCAGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U7FJ92

Antitoxin

Source ID Structure
AlphaFold DB A0A7U7IQA2

References