Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2086081..2086344 Replicon chromosome
Accession NZ_CP009828
Organism Staphylococcus aureus strain MS4

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NI36_RS10520 Protein ID WP_001802298.1
Coordinates 2086240..2086344 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2086081..2086245 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NI36_RS10500 2082318..2082983 - 666 WP_001024088.1 SDR family oxidoreductase -
NI36_RS10505 2083135..2083455 + 321 WP_000139802.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NI36_RS10510 2083457..2084434 + 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
NI36_RS10515 2084700..2085791 + 1092 WP_000495695.1 hypothetical protein -
- 2086081..2086245 + 165 - - Antitoxin
NI36_RS10520 2086240..2086344 - 105 WP_001802298.1 hypothetical protein Toxin
NI36_RS14495 2086505..2086988 - 484 Protein_2007 recombinase family protein -
NI36_RS14190 2087031..2088167 - 1137 Protein_2008 SAP domain-containing protein -
NI36_RS10540 2088456..2088548 + 93 WP_031844941.1 hypothetical protein -
NI36_RS10545 2089243..2090100 - 858 WP_000370919.1 Cof-type HAD-IIB family hydrolase -
NI36_RS10550 2090168..2090950 - 783 WP_000908190.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T49905 WP_001802298.1 NZ_CP009828:c2086344-2086240 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T49905 NZ_CP009828:c2086344-2086240 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT49905 NZ_CP009828:2086081-2086245 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References