49876

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 896684..897390 Replicon chromosome
Accession NZ_CP009823
Organism Xylella fastidiosa strain J1a12

Toxin (Protein)


Gene name mqsR Uniprot ID Q9PAL4
Locus tag OY18_RS04400 Protein ID WP_010894925.1
Coordinates 897088..897390 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag OY18_RS04395 Protein ID WP_060872143.1
Coordinates 896684..897085 (-) Length 134 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OY18_RS04365 (OY18_04090) 892514..894394 + 1881 WP_088569678.1 phage major capsid protein -
OY18_RS04370 (OY18_04095) 894412..894672 + 261 WP_010893239.1 hypothetical protein -
OY18_RS04375 (OY18_04100) 894672..894995 + 324 WP_060872404.1 hypothetical protein -
OY18_RS04380 (OY18_04105) 894992..895513 + 522 WP_010893241.1 hypothetical protein -
OY18_RS04385 (OY18_04110) 895489..896031 + 543 WP_042462905.1 hypothetical protein -
OY18_RS04390 (OY18_04115) 896028..896615 + 588 WP_060872144.1 phage baseplate assembly protein V -
OY18_RS04395 (OY18_04120) 896684..897085 - 402 WP_060872143.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
OY18_RS04400 (OY18_04125) 897088..897390 - 303 WP_010894925.1 type II toxin-antitoxin system MqsR family toxin Toxin
OY18_RS04405 (OY18_04130) 897512..897793 - 282 WP_060872142.1 type II toxin-antitoxin system YafQ family toxin -
OY18_RS04410 (OY18_04135) 897780..898043 - 264 WP_060872141.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
OY18_RS04415 (OY18_04140) 898169..898531 + 363 WP_229926338.1 GPW/gp25 family protein -
OY18_RS04420 (OY18_04145) 898531..899424 + 894 WP_060871906.1 baseplate J/gp47 family protein -
OY18_RS04425 (OY18_04150) 899417..899974 + 558 WP_060871910.1 phage tail protein I -
OY18_RS14920 899982..900476 + 495 WP_229926339.1 hypothetical protein -
OY18_RS04430 (OY18_04155) 900488..901573 + 1086 WP_229926340.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 790250..953208 162958


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-99)

Antitoxin

(74-127)


Sequences


Toxin        


Download         Length: 101 a.a.        Molecular weight: 10958.74 Da        Isoelectric Point: 8.0251

>T49876 WP_010894925.1 NZ_CP009823:c897390-897088 [Xylella fastidiosa]
MEKGTPHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCTVVLALTSADFYKSMTTYADHTVFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL

Download         Length: 303 bp

>T49876 NZ_CP009823:c897390-897088 [Xylella fastidiosa]
ATGGAGAAAGGCACACCCCACTACAAGCTACCAGTCGTCAAAGCCTTGGTAAAAGCTGGCAAGGTCAGGGCTACAGCGAC
CGCCTACCAAGGAGCACGTGAGCTTGGCATCAAAGATTTAACTGGAATGTGCACCGTTGTCTTGGCGCTCACGTCTGCCG
ACTTCTACAAGAGCATGACGACCTACGCGGATCACACAGTATTCCAGGATGTGTACCACGCCAAGACGGCAAGCGGTGAT
GAGGTGTACCTGAAGTTAACTGTCATTGATGACGTGTTGATTGTTTCCTTCAAGGAGTTATGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 15004.12 Da        Isoelectric Point: 7.1650

>AT49876 WP_060872143.1 NZ_CP009823:c897085-896684 [Xylella fastidiosa]
MRCPCCGAAELIHDTRDMLYTYKSETTSIPTVTGDFCPACGEVVLDREHGDRYSELVGLFQRQVNSAYVDPGYITKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLFKLLDRHPDLLNEVKSF

Download         Length: 402 bp

>AT49876 NZ_CP009823:c897085-896684 [Xylella fastidiosa]
ATGAGATGTCCATGCTGCGGCGCGGCAGAACTGATCCACGACACGCGCGACATGCTTTACACCTATAAGAGCGAAACTAC
TAGTATCCCAACGGTGACCGGCGACTTCTGCCCGGCGTGTGGCGAAGTCGTCTTGGACCGTGAACATGGTGATCGTTACA
GCGAATTGGTCGGCTTGTTCCAACGTCAGGTGAATTCGGCCTACGTCGATCCTGGTTACATTACCAAGGTACGCCGGAAG
CTTGATCTCGACCAGCGGCAAGCTGCCGAACTGTTCGGTGGTGGTGTTAATGCTTTCTCACGTTACGAGAACGGTAAAAC
CAAGCCGCCGCTGTCTTTGGTTAAGTTATTCAAGCTTCTGGATCGCCACCCCGATTTGCTCAACGAAGTGAAGAGTTTCT
AA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB Q9PAL4


Antitoxin

Source ID Structure

References