Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mqsRA (relBE)/MqsR-MqsA |
Location | 896684..897390 | Replicon | chromosome |
Accession | NZ_CP009823 | ||
Organism | Xylella fastidiosa strain J1a12 |
Toxin (Protein)
Gene name | mqsR | Uniprot ID | Q9PAL4 |
Locus tag | OY18_RS04400 | Protein ID | WP_010894925.1 |
Coordinates | 897088..897390 (-) | Length | 101 a.a. |
Antitoxin (Protein)
Gene name | mqsA | Uniprot ID | - |
Locus tag | OY18_RS04395 | Protein ID | WP_060872143.1 |
Coordinates | 896684..897085 (-) | Length | 134 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OY18_RS04365 (OY18_04090) | 892514..894394 | + | 1881 | WP_088569678.1 | phage major capsid protein | - |
OY18_RS04370 (OY18_04095) | 894412..894672 | + | 261 | WP_010893239.1 | hypothetical protein | - |
OY18_RS04375 (OY18_04100) | 894672..894995 | + | 324 | WP_060872404.1 | hypothetical protein | - |
OY18_RS04380 (OY18_04105) | 894992..895513 | + | 522 | WP_010893241.1 | hypothetical protein | - |
OY18_RS04385 (OY18_04110) | 895489..896031 | + | 543 | WP_042462905.1 | hypothetical protein | - |
OY18_RS04390 (OY18_04115) | 896028..896615 | + | 588 | WP_060872144.1 | phage baseplate assembly protein V | - |
OY18_RS04395 (OY18_04120) | 896684..897085 | - | 402 | WP_060872143.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
OY18_RS04400 (OY18_04125) | 897088..897390 | - | 303 | WP_010894925.1 | type II toxin-antitoxin system MqsR family toxin | Toxin |
OY18_RS04405 (OY18_04130) | 897512..897793 | - | 282 | WP_060872142.1 | type II toxin-antitoxin system YafQ family toxin | - |
OY18_RS04410 (OY18_04135) | 897780..898043 | - | 264 | WP_060872141.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
OY18_RS04415 (OY18_04140) | 898169..898531 | + | 363 | WP_229926338.1 | GPW/gp25 family protein | - |
OY18_RS04420 (OY18_04145) | 898531..899424 | + | 894 | WP_060871906.1 | baseplate J/gp47 family protein | - |
OY18_RS04425 (OY18_04150) | 899417..899974 | + | 558 | WP_060871910.1 | phage tail protein I | - |
OY18_RS14920 | 899982..900476 | + | 495 | WP_229926339.1 | hypothetical protein | - |
OY18_RS04430 (OY18_04155) | 900488..901573 | + | 1086 | WP_229926340.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 790250..953208 | 162958 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 10958.74 Da Isoelectric Point: 8.0251
>T49876 WP_010894925.1 NZ_CP009823:c897390-897088 [Xylella fastidiosa]
MEKGTPHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCTVVLALTSADFYKSMTTYADHTVFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL
MEKGTPHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCTVVLALTSADFYKSMTTYADHTVFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL
Download Length: 303 bp
>T49876 NZ_CP009823:c897390-897088 [Xylella fastidiosa]
ATGGAGAAAGGCACACCCCACTACAAGCTACCAGTCGTCAAAGCCTTGGTAAAAGCTGGCAAGGTCAGGGCTACAGCGAC
CGCCTACCAAGGAGCACGTGAGCTTGGCATCAAAGATTTAACTGGAATGTGCACCGTTGTCTTGGCGCTCACGTCTGCCG
ACTTCTACAAGAGCATGACGACCTACGCGGATCACACAGTATTCCAGGATGTGTACCACGCCAAGACGGCAAGCGGTGAT
GAGGTGTACCTGAAGTTAACTGTCATTGATGACGTGTTGATTGTTTCCTTCAAGGAGTTATGA
ATGGAGAAAGGCACACCCCACTACAAGCTACCAGTCGTCAAAGCCTTGGTAAAAGCTGGCAAGGTCAGGGCTACAGCGAC
CGCCTACCAAGGAGCACGTGAGCTTGGCATCAAAGATTTAACTGGAATGTGCACCGTTGTCTTGGCGCTCACGTCTGCCG
ACTTCTACAAGAGCATGACGACCTACGCGGATCACACAGTATTCCAGGATGTGTACCACGCCAAGACGGCAAGCGGTGAT
GAGGTGTACCTGAAGTTAACTGTCATTGATGACGTGTTGATTGTTTCCTTCAAGGAGTTATGA
Antitoxin
Download Length: 134 a.a. Molecular weight: 15004.12 Da Isoelectric Point: 7.1650
>AT49876 WP_060872143.1 NZ_CP009823:c897085-896684 [Xylella fastidiosa]
MRCPCCGAAELIHDTRDMLYTYKSETTSIPTVTGDFCPACGEVVLDREHGDRYSELVGLFQRQVNSAYVDPGYITKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLFKLLDRHPDLLNEVKSF
MRCPCCGAAELIHDTRDMLYTYKSETTSIPTVTGDFCPACGEVVLDREHGDRYSELVGLFQRQVNSAYVDPGYITKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLFKLLDRHPDLLNEVKSF
Download Length: 402 bp
>AT49876 NZ_CP009823:c897085-896684 [Xylella fastidiosa]
ATGAGATGTCCATGCTGCGGCGCGGCAGAACTGATCCACGACACGCGCGACATGCTTTACACCTATAAGAGCGAAACTAC
TAGTATCCCAACGGTGACCGGCGACTTCTGCCCGGCGTGTGGCGAAGTCGTCTTGGACCGTGAACATGGTGATCGTTACA
GCGAATTGGTCGGCTTGTTCCAACGTCAGGTGAATTCGGCCTACGTCGATCCTGGTTACATTACCAAGGTACGCCGGAAG
CTTGATCTCGACCAGCGGCAAGCTGCCGAACTGTTCGGTGGTGGTGTTAATGCTTTCTCACGTTACGAGAACGGTAAAAC
CAAGCCGCCGCTGTCTTTGGTTAAGTTATTCAAGCTTCTGGATCGCCACCCCGATTTGCTCAACGAAGTGAAGAGTTTCT
AA
ATGAGATGTCCATGCTGCGGCGCGGCAGAACTGATCCACGACACGCGCGACATGCTTTACACCTATAAGAGCGAAACTAC
TAGTATCCCAACGGTGACCGGCGACTTCTGCCCGGCGTGTGGCGAAGTCGTCTTGGACCGTGAACATGGTGATCGTTACA
GCGAATTGGTCGGCTTGTTCCAACGTCAGGTGAATTCGGCCTACGTCGATCCTGGTTACATTACCAAGGTACGCCGGAAG
CTTGATCTCGACCAGCGGCAAGCTGCCGAACTGTTCGGTGGTGGTGTTAATGCTTTCTCACGTTACGAGAACGGTAAAAC
CAAGCCGCCGCTGTCTTTGGTTAAGTTATTCAAGCTTCTGGATCGCCACCCCGATTTGCTCAACGAAGTGAAGAGTTTCT
AA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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