Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 4467204..4468039 Replicon chromosome
Accession NZ_CP009769
Organism Pectobacterium brasiliense strain BC1

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag NC16_RS20390 Protein ID WP_075278437.1
Coordinates 4467204..4467689 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag NC16_RS20395 Protein ID WP_075278438.1
Coordinates 4467695..4468039 (-) Length 115 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NC16_RS20370 4462756..4464189 - 1434 WP_075278434.1 FtsX-like permease family protein -
NC16_RS20375 4464186..4464878 - 693 WP_014916886.1 ABC transporter ATP-binding protein -
NC16_RS20380 4464887..4465366 - 480 WP_075278435.1 hypothetical protein -
NC16_RS20385 4465379..4467124 - 1746 WP_075278436.1 alkaline phosphatase -
NC16_RS20390 4467204..4467689 - 486 WP_075278437.1 type II toxin-antitoxin system YhaV family toxin Toxin
NC16_RS20395 4467695..4468039 - 345 WP_075278438.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
NC16_RS20400 4468228..4471338 - 3111 WP_075278439.1 multidrug efflux RND transporter permease AcrD -
NC16_RS20405 4471519..4472286 - 768 WP_040033313.1 pimeloyl-ACP methyl ester esterase BioH -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-148)

Antitoxin

PrlF antitoxin

(15-113)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 18674.35 Da        Isoelectric Point: 9.3704

>T49663 WP_075278437.1 NZ_CP009769:c4467689-4467204 [Pectobacterium brasiliense]
MVDKRVINGWQLFTHPCFDAQFESLIVEVEQLRKKHPESYQKKQATKLLAAIVKVIRTEICGDPSQTKFRQGDTLGEGNK
HWFRAKFLGQYRLFFRYSERHKTIILAWVNDSDTKRAYGDQHDAYKVFSGMLASGNPPGDWEQLLAESHSEAMLTQMLVR
P

Download         Length: 486 bp

>T49663 NZ_CP009769:c4467689-4467204 [Pectobacterium brasiliense]
ATGGTTGATAAGCGAGTAATAAATGGGTGGCAGCTATTTACGCATCCTTGTTTTGATGCGCAGTTTGAGTCTCTTATTGT
TGAAGTTGAGCAGTTGCGTAAGAAACATCCAGAATCTTATCAGAAAAAGCAGGCAACTAAGCTATTGGCTGCAATAGTTA
AAGTCATCCGTACTGAGATTTGTGGCGATCCGTCCCAAACGAAATTTAGACAAGGCGATACGCTAGGCGAAGGTAATAAA
CATTGGTTCAGGGCAAAATTTCTGGGTCAGTATCGGTTATTTTTTCGCTATAGCGAGAGACATAAAACTATCATCCTTGC
CTGGGTCAATGATTCAGACACTAAACGAGCATATGGCGATCAGCATGATGCTTATAAAGTTTTTAGCGGCATGCTAGCAA
GCGGGAATCCGCCGGGAGATTGGGAGCAACTGCTCGCTGAATCCCATAGTGAGGCCATGCTTACGCAAATGCTCGTGCGG
CCGTAA

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12817.41 Da        Isoelectric Point: 4.4510

>AT49663 WP_075278438.1 NZ_CP009769:c4468039-4467695 [Pectobacterium brasiliense]
MFDLKSADVLLRADSRLTARSQTTIPSSVRDAMNLQPGEYIHYSVLPGGQVLISRREEAIDDDPVIHHFLHFLAEDMQRH
PENIKPFDQSLMSRASVLTAGMDIDLDAPLTDDE

Download         Length: 345 bp

>AT49663 NZ_CP009769:c4468039-4467695 [Pectobacterium brasiliense]
ATGTTTGATTTAAAATCAGCGGATGTGTTGTTGCGCGCCGATAGTCGCTTAACGGCGCGTAGTCAGACAACGATTCCATC
GTCTGTGCGTGATGCAATGAACCTGCAACCTGGGGAGTACATTCATTATAGCGTGCTACCGGGGGGGCAAGTGCTGATCA
GTCGGCGTGAAGAGGCGATAGATGATGACCCCGTTATTCATCACTTTTTGCATTTTTTGGCTGAAGATATGCAACGTCAT
CCAGAAAATATTAAGCCGTTTGATCAATCGCTTATGTCACGTGCCAGTGTGTTAACCGCAGGGATGGATATTGATCTGGA
TGCACCGCTTACTGACGACGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References