Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2710153..2710337 Replicon chromosome
Accession NZ_CP009681
Organism Staphylococcus aureus strain Gv69

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag SAGV69_RS14220 Protein ID WP_000482650.1
Coordinates 2710230..2710337 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2710153..2710213 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAGV69_RS14195 2705683..2705850 - 168 WP_001790576.1 hypothetical protein -
SAGV69_RS14205 2706081..2707814 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
SAGV69_RS14210 2707839..2709602 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2710153..2710213 + 61 - - Antitoxin
SAGV69_RS14220 2710230..2710337 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
SAGV69_RS14225 2710470..2710856 - 387 WP_000779358.1 flippase GtxA -
SAGV69_RS14230 2711124..2712266 + 1143 WP_001176863.1 glycerate kinase -
SAGV69_RS14235 2712326..2712985 + 660 WP_000831298.1 membrane protein -
SAGV69_RS14240 2713167..2714378 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
SAGV69_RS14245 2714501..2714974 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T49424 WP_000482650.1 NZ_CP009681:c2710337-2710230 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T49424 NZ_CP009681:c2710337-2710230 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT49424 NZ_CP009681:2710153-2710213 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References