Detailed information of TA system TA049406

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 579265..579447
• Replicon: chromosome
• Accession: NZ_CP009681
• Organism: Staphylococcus aureus strain Gv69

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAGV69_RS16915
• Protein ID: WP_001801861.1
• Coordinates: 579352..579447 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	579265..579324 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAGV69_RS03025	576727..577899	+	1173	Protein_560	IS256 family transposase	-
SAGV69_RS03035	578403..578780	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
SAGV69_RS16130	578974..579150	+	177	Protein_562	transposase	-
SAGV69_RS03040	579128..579229	-	102	WP_001791893.1	hypothetical protein	-
-	579265..579324	+	60	-	-	Antitoxin
SAGV69_RS16915	579352..579447	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
SAGV69_RS03045	579650..579793	+	144	WP_001549059.1	transposase	-
SAGV69_RS03055	580397..580780	+	384	WP_000070811.1	hypothetical protein	-
SAGV69_RS03060	580791..580967	+	177	WP_000375476.1	hypothetical protein	-
SAGV69_RS03065	580969..581154	+	186	WP_000809857.1	hypothetical protein	-
SAGV69_RS03070	581268..581909	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
SAGV69_RS03075	582127..582678	-	552	WP_000414205.1	hypothetical protein	-
SAGV69_RS03080	582776..583120	-	345	WP_000627551.1	DUF3969 family protein	-
SAGV69_RS03085	583161..583787	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	572048..581154	9106

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T49406 WP_001801861.1 NZ_CP009681:c579447-579352 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T49406 NZ_CP009681:c579447-579352 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT49406 NZ_CP009681:579265-579324 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin