49333

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1698300..1698459 Replicon chromosome
Accession NZ_CP009623
Organism Staphylococcus agnetis strain 908

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag EP23_RS20660 Protein ID WP_107365594.1
Coordinates 1698358..1698459 (-) Length 34 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1698300..1698333 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EP23_RS20635 1694132..1695571 - 1440 WP_060551883.1 alkaline phosphatase -
EP23_RS20640 1695790..1696440 + 651 WP_060551884.1 zinc ribbon domain-containing protein -
EP23_RS20645 1696513..1697127 - 615 WP_060551885.1 DedA family protein -
EP23_RS20650 1697245..1697655 - 411 WP_060551886.1 hypothetical protein -
EP23_RS20655 1697917..1698189 + 273 WP_060551887.1 DUF2316 family protein -
- 1698300..1698333 + 34 - - Antitoxin
EP23_RS20660 1698358..1698459 - 102 WP_107365594.1 type I toxin-antitoxin system Fst family toxin Toxin
EP23_RS20665 1698594..1699604 - 1011 WP_060551888.1 HoxN/HupN/NixA family nickel/cobalt transporter -
EP23_RS20670 1699818..1700495 + 678 WP_037565806.1 response regulator transcription factor -
EP23_RS20675 1700488..1701972 + 1485 WP_060551889.1 HAMP domain-containing histidine kinase -
EP23_RS20680 1702193..1702633 - 441 WP_060551890.1 antibiotic biosynthesis monooxygenase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 34 a.a.        Molecular weight: 3789.56 Da        Isoelectric Point: 10.7732

>T49333 WP_107365594.1 NZ_CP009623:c1698459-1698358 [Staphylococcus agnetis]
MLDILVHITTTIISGCIVTLFAHWLRTRGNKHK

Download         Length: 102 bp

>T49333 NZ_CP009623:c1698459-1698358 [Staphylococcus agnetis]
ATGTTAGATATCCTTGTTCACATCACGACCACGATCATCAGTGGTTGTATTGTTACGCTTTTTGCGCATTGGCTACGCAC
GCGTGGCAATAAGCATAAATAG

Antitoxin


Download         Length: 34 bp

>AT49333 NZ_CP009623:1698300-1698333 [Staphylococcus agnetis]
CACCAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References