Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
| Location | 61489..62146 | Replicon | plasmid pCFSAN000934_02 |
| Accession | NZ_CP009567 | ||
| Organism | Salmonella enterica subsp. enterica serovar Newport str. CVM 22462 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | U3PDC3 |
| Locus tag | SEEN462_RS00895 | Protein ID | WP_000270043.1 |
| Coordinates | 61489..61839 (+) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | SEEN462_RS00900 | Protein ID | WP_000124640.1 |
| Coordinates | 61844..62146 (+) | Length | 101 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SEEN462_RS00845 | 56800..56979 | + | 180 | Protein_62 | helix-turn-helix transcriptional regulator | - |
| SEEN462_RS00850 | 57044..57748 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| SEEN462_RS00855 | 57963..58460 | - | 498 | WP_000062185.1 | hypothetical protein | - |
| SEEN462_RS00860 | 58463..58951 | - | 489 | WP_001273096.1 | DUF1643 domain-containing protein | - |
| SEEN462_RS00865 | 59048..59383 | + | 336 | WP_000683476.1 | hypothetical protein | - |
| SEEN462_RS00870 | 59398..59868 | - | 471 | WP_001281821.1 | hypothetical protein | - |
| SEEN462_RS27050 | 59861..60232 | - | 372 | WP_000516916.1 | hypothetical protein | - |
| SEEN462_RS27055 | 60243..60437 | - | 195 | WP_000343597.1 | hypothetical protein | - |
| SEEN462_RS00890 | 60778..61326 | - | 549 | WP_001061574.1 | transcriptional regulator | - |
| SEEN462_RS00895 | 61489..61839 | + | 351 | WP_000270043.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| SEEN462_RS00900 | 61844..62146 | + | 303 | WP_000124640.1 | XRE family transcriptional regulator | Antitoxin |
| SEEN462_RS00905 | 62173..62466 | - | 294 | WP_001239997.1 | chromosome segregation protein ParM | - |
| SEEN462_RS00910 | 62554..62826 | - | 273 | WP_001043047.1 | HU family DNA-binding protein | - |
| SEEN462_RS00915 | 62884..63411 | - | 528 | WP_001236377.1 | thermonuclease family protein | - |
| SEEN462_RS00925 | 63642..64499 | - | 858 | WP_001167032.1 | hypothetical protein | - |
| SEEN462_RS00930 | 64486..64716 | - | 231 | WP_000972663.1 | hypothetical protein | - |
| SEEN462_RS00935 | 64716..65234 | - | 519 | WP_000210756.1 | nitrite reductase | - |
| SEEN462_RS00940 | 65231..65677 | - | 447 | WP_000919345.1 | Fe3+-siderophore ABC transporter permease | - |
| SEEN462_RS00945 | 65677..66036 | - | 360 | WP_000422768.1 | hypothetical protein | - |
| SEEN462_RS00950 | 66093..66521 | - | 429 | WP_000591074.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..158521 | 158521 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 15014.38 Da Isoelectric Point: 12.8644
>T49287 WP_000270043.1 NZ_CP009567:61489-61839 [Salmonella enterica subsp. enterica serovar Newport str. CVM 22462]
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Download Length: 351 bp
>T49287 NZ_CP009567:61489-61839 [Salmonella enterica subsp. enterica serovar Newport str. CVM 22462]
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Antitoxin
Download Length: 101 a.a. Molecular weight: 12963.60 Da Isoelectric Point: 12.8000
>AT49287 WP_000124640.1 NZ_CP009567:61844-62146 [Salmonella enterica subsp. enterica serovar Newport str. CVM 22462]
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Download Length: 303 bp
>AT49287 NZ_CP009567:61844-62146 [Salmonella enterica subsp. enterica serovar Newport str. CVM 22462]
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Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|