Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2291626..2291842 Replicon chromosome
Accession NZ_CP009554
Organism Staphylococcus aureus strain FORC_001

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag FORC1_RS11590 Protein ID WP_073392962.1
Coordinates 2291738..2291842 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2291626..2291681 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC1_RS11570 2286719..2287039 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FORC1_RS11575 2287041..2288021 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
FORC1_RS11580 2288287..2289378 + 1092 WP_000495684.1 hypothetical protein -
FORC1_RS11585 2289666..2291312 + 1647 WP_042363653.1 IS1182-like element ISSau3 family transposase -
- 2291626..2291681 + 56 - - Antitoxin
FORC1_RS11590 2291738..2291842 - 105 WP_073392962.1 hypothetical protein Toxin
FORC1_RS15255 2292522..2292680 + 159 WP_001792784.1 hypothetical protein -
FORC1_RS11595 2293339..2294196 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
FORC1_RS11600 2294264..2295046 - 783 WP_042363654.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2289666..2291312 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T49275 WP_073392962.1 NZ_CP009554:c2291842-2291738 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T49275 NZ_CP009554:c2291842-2291738 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT49275 NZ_CP009554:2291626-2291681 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References