Detailed information of TA system TA049267

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1944714..1944894
• Replicon: chromosome
• Accession: NZ_CP009554
• Organism: Staphylococcus aureus strain FORC_001

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: FORC1_RS15560
• Protein ID: WP_001801861.1
• Coordinates: 1944714..1944809 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1944837..1944894 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FORC1_RS09465	1939858..1940484	+	627	WP_000669038.1	hypothetical protein	-
FORC1_RS09470	1940525..1940869	+	345	WP_000627550.1	DUF3969 family protein	-
FORC1_RS09475	1940967..1941539	+	573	WP_000414222.1	hypothetical protein	-
FORC1_RS09480	1941688..1943055	-	1368	WP_001093574.1	FRG domain-containing protein	-
FORC1_RS09485	1943055..1943624	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
FORC1_RS09490	1943817..1944263	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
FORC1_RS15560	1944714..1944809	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1944837..1944894	-	58	-	-	Antitoxin
FORC1_RS09495	1944932..1945033	+	102	WP_001791232.1	hypothetical protein	-
FORC1_RS09500	1945208..1945651	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
FORC1_RS09505	1945651..1946094	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
FORC1_RS15120	1946094..1946536	-	443	Protein_1840	DUF1433 domain-containing protein	-
FORC1_RS09515	1947061..1949480	+	2420	Protein_1841	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T49267 WP_001801861.1 NZ_CP009554:1944714-1944809 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T49267 NZ_CP009554:1944714-1944809 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT49267 NZ_CP009554:c1944894-1944837 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin