49209

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 298176..298762 Replicon chromosome
Accession NZ_CP009533
Organism Pseudomonas rhizosphaerae strain DSM 16299

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag LT40_RS21035 Protein ID WP_084139697.1
Coordinates 298484..298762 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag LT40_RS01395 Protein ID WP_043185531.1
Coordinates 298176..298475 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LT40_RS01365 293612..294301 - 690 WP_043185515.1 crotonase/enoyl-CoA hydratase family protein -
LT40_RS01375 294745..295500 - 756 WP_052393178.1 class I SAM-dependent methyltransferase -
LT40_RS01380 295569..296099 + 531 WP_158497434.1 helix-turn-helix transcriptional regulator -
LT40_RS01385 296137..296835 + 699 WP_043185522.1 SDR family NAD(P)-dependent oxidoreductase -
LT40_RS01390 296849..297814 - 966 WP_043185526.1 DMT family transporter -
LT40_RS01395 298176..298475 - 300 WP_043185531.1 HigA family addiction module antidote protein Antitoxin
LT40_RS21035 298484..298762 - 279 WP_084139697.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LT40_RS01400 298855..299490 - 636 WP_043185534.1 hydrolase -
LT40_RS01405 299774..301756 + 1983 WP_043185537.1 methyl-accepting chemotaxis protein -
LT40_RS01410 301801..303366 - 1566 WP_043185541.1 diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(9-92)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-70)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10654.94 Da        Isoelectric Point: 6.7104

>T49209 WP_084139697.1 NZ_CP009533:c298762-298484 [Pseudomonas rhizosphaerae]
MIRSFACADTEALFTTGRTRRWPDIKQVAERKLAALDAANELRDLRSPPGNRLHSLEDDRRGQHSISINMQWRVCFTWTE
SGPENVEIVDYH

Download         Length: 279 bp

>T49209 NZ_CP009533:c298762-298484 [Pseudomonas rhizosphaerae]
ATGATCCGAAGCTTTGCATGTGCCGACACGGAAGCGCTTTTTACCACTGGCAGAACCAGGCGCTGGCCCGACATCAAGCA
AGTCGCAGAGCGAAAACTGGCTGCACTGGATGCAGCAAACGAGCTTCGAGACTTGCGGTCACCGCCTGGAAATCGACTTC
ACTCCCTAGAGGATGACAGACGGGGACAGCACAGCATTAGTATCAACATGCAATGGCGAGTCTGTTTCACATGGACCGAA
AGCGGCCCCGAAAACGTTGAAATTGTCGATTATCACTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10893.45 Da        Isoelectric Point: 5.0872

>AT49209 WP_043185531.1 NZ_CP009533:c298475-298176 [Pseudomonas rhizosphaerae]
MFKNGMRPVHPGEVLREDFQSEMGFSAAALARALNVSTPTVNNILLERGGVSADMALRLAICLDTTPEFWLNLQTAYELR
KAEQEHGDEIAAAVHRLVA

Download         Length: 300 bp

>AT49209 NZ_CP009533:c298475-298176 [Pseudomonas rhizosphaerae]
ATGTTCAAGAATGGCATGCGTCCGGTACATCCTGGCGAGGTTCTTCGCGAGGACTTCCAGAGCGAGATGGGCTTTAGCGC
TGCTGCCTTGGCCCGTGCTTTGAATGTCTCCACGCCCACCGTAAATAACATTTTACTTGAGCGCGGCGGCGTTTCTGCTG
ACATGGCTCTGCGATTGGCCATCTGCCTGGATACAACTCCAGAGTTCTGGCTCAACCTACAAACAGCGTACGAGCTACGC
AAGGCAGAGCAAGAGCACGGAGATGAGATCGCCGCTGCGGTACATCGCCTGGTTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References