Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 122364..123066 Replicon chromosome
Accession NZ_CP009459
Organism Cedecea neteri strain ND14a

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag LH86_RS00565 Protein ID WP_039297470.1
Coordinates 122767..123066 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag LH86_RS00560 Protein ID WP_039297468.1
Coordinates 122364..122765 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LH86_RS00530 118031..118336 + 306 WP_039297454.1 chaperone modulator CbpM -
LH86_RS00535 118486..118845 + 360 WP_039286956.1 hypothetical protein -
LH86_RS00540 118893..119678 - 786 WP_039297457.1 helix-turn-helix transcriptional regulator -
LH86_RS00545 119771..120637 + 867 WP_039297460.1 EamA family transporter -
LH86_RS00550 120634..121314 - 681 WP_039297463.1 nitroreductase -
LH86_RS00555 121435..122367 + 933 WP_039297465.1 LysR family transcriptional regulator -
LH86_RS00560 122364..122765 - 402 WP_039297468.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
LH86_RS00565 122767..123066 - 300 WP_039297470.1 type II toxin-antitoxin system MqsR family toxin Toxin
LH86_RS00570 123183..124319 - 1137 WP_039297473.1 alpha/beta fold hydrolase -
LH86_RS00575 124507..125019 + 513 WP_039297475.1 helix-turn-helix transcriptional regulator -
LH86_RS00580 125055..126008 + 954 WP_197061695.1 2-dehydropantoate 2-reductase -
LH86_RS00585 126018..126866 + 849 WP_039297480.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-98)

Antitoxin

Zinc finger, MqsA-type

(3-46)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11202.01 Da        Isoelectric Point: 9.6288

>T49083 WP_039297470.1 NZ_CP009459:c123066-122767 [Cedecea neteri]
MEKRMPHTRLNFIHSMVRAGNVAITHTALASGAALGFTAKRDFFDVVLALSPRDFEKSMTAYHDHTLWHEVYRPVFNGQS
LYIKLVVHGGVLIVSFKEC

Download         Length: 300 bp

>T49083 NZ_CP009459:c123066-122767 [Cedecea neteri]
ATGGAGAAGAGAATGCCCCATACCCGCCTGAATTTTATTCACTCGATGGTCAGAGCAGGCAATGTTGCGATAACCCATAC
CGCATTAGCGAGTGGCGCAGCGCTTGGTTTTACCGCAAAGCGGGATTTTTTCGACGTCGTGCTGGCGCTTAGCCCGAGGG
ATTTCGAAAAAAGTATGACGGCTTACCACGATCATACCCTCTGGCATGAGGTCTACCGGCCAGTTTTCAATGGGCAGTCA
CTTTATATAAAGCTGGTTGTTCATGGCGGAGTGCTTATCGTGTCATTTAAGGAGTGCTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14619.55 Da        Isoelectric Point: 6.3250

>AT49083 WP_039297468.1 NZ_CP009459:c122765-122364 [Cedecea neteri]
MKCPVCGGENAVHEARDIHYEYKGHSKTFPGVTGLHCNDCGEIVFADGEGDAYFSGMLAFNREVNAQEVDPAFIAAVRKR
LKLNQAQAAEFFGGGANAFSRYETGRIAPPRPLILLFKALDKHPELFDELKTS

Download         Length: 402 bp

>AT49083 NZ_CP009459:c122765-122364 [Cedecea neteri]
ATGAAATGCCCTGTGTGCGGCGGCGAAAATGCCGTTCATGAAGCCCGCGATATTCACTACGAATACAAAGGCCATTCCAA
AACGTTTCCGGGCGTGACCGGGCTGCATTGCAATGACTGCGGTGAAATTGTTTTCGCCGATGGGGAAGGTGATGCCTATT
TCAGCGGCATGCTGGCGTTTAACCGCGAAGTGAACGCCCAGGAGGTCGACCCCGCCTTTATTGCCGCCGTGCGTAAACGC
CTGAAGCTGAATCAGGCGCAGGCCGCCGAATTTTTTGGCGGGGGAGCCAATGCGTTCAGCCGTTATGAAACGGGGCGCAT
TGCCCCTCCGCGGCCGCTGATCCTGCTGTTTAAAGCGCTGGATAAACACCCTGAGCTTTTTGACGAGCTCAAAACGAGCT
AA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References