Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 128793..129495 Replicon chromosome
Accession NZ_CP009458
Organism Cedecea neteri strain M006

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag LH23_RS00600 Protein ID WP_039286975.1
Coordinates 129196..129495 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag LH23_RS00595 Protein ID WP_039286972.1
Coordinates 128793..129194 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LH23_RS00565 124461..124766 + 306 WP_039286953.1 chaperone modulator CbpM -
LH23_RS00570 124916..125275 + 360 WP_039286956.1 hypothetical protein -
LH23_RS00575 125323..126108 - 786 WP_039286961.1 helix-turn-helix transcriptional regulator -
LH23_RS00580 126201..127067 + 867 WP_039286963.1 EamA family transporter -
LH23_RS00585 127064..127744 - 681 WP_039286966.1 nitroreductase -
LH23_RS00590 127864..128796 + 933 WP_039286969.1 LysR family transcriptional regulator -
LH23_RS00595 128793..129194 - 402 WP_039286972.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
LH23_RS00600 129196..129495 - 300 WP_039286975.1 type II toxin-antitoxin system MqsR family toxin Toxin
LH23_RS00605 129612..130748 - 1137 WP_039286978.1 alpha/beta fold hydrolase -
LH23_RS00610 130936..131448 + 513 WP_052050090.1 helix-turn-helix transcriptional regulator -
LH23_RS00615 131381..132436 + 1056 WP_197062501.1 2-dehydropantoate 2-reductase -
LH23_RS00620 132446..133294 + 849 WP_039286984.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-98)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-127)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11184.90 Da        Isoelectric Point: 9.8653

>T49068 WP_039286975.1 NZ_CP009458:c129495-129196 [Cedecea neteri]
MEKRTPHTRLSFIHSMVRSGNVAITHTALASGAALGFTAKRDFFDVVLALSPRDFEKSMTAYHDHTLWHEVYRPVFNGQS
LYIKLIVYGGVLIVSFKES

Download         Length: 300 bp

>T49068 NZ_CP009458:c129495-129196 [Cedecea neteri]
ATGGAGAAGAGAACGCCCCATACCCGCCTGAGTTTTATTCACTCGATGGTCAGATCGGGCAATGTTGCGATAACCCATAC
CGCATTAGCGAGTGGCGCAGCGCTTGGTTTTACCGCAAAGCGGGATTTTTTCGACGTCGTGCTGGCGCTTAGCCCCAGGG
ATTTCGAAAAAAGTATGACGGCTTACCACGATCATACCCTCTGGCATGAGGTCTACCGGCCAGTCTTCAATGGGCAGTCG
CTCTATATAAAGCTGATTGTTTATGGCGGAGTGCTTATCGTGTCATTTAAGGAGTCCTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14656.61 Da        Isoelectric Point: 6.4824

>AT49068 WP_039286972.1 NZ_CP009458:c129194-128793 [Cedecea neteri]
MKCPVCGGEHAVHEARDIHYEYKGHSKTFPGVTGLHCNDCGEIVFADGEGEAYFSGMLAFNREVNAQEVDPAFIAAVRKR
LKLNQAQAAEFFGGGANAFSRYETGRIAPPRPLILLFKALDKHPELFDELKTS

Download         Length: 402 bp

>AT49068 NZ_CP009458:c129194-128793 [Cedecea neteri]
ATGAAATGCCCTGTGTGCGGCGGCGAACATGCCGTTCATGAAGCCCGCGATATTCACTACGAATACAAAGGCCATTCCAA
AACGTTTCCGGGCGTGACCGGGCTGCACTGCAATGACTGCGGTGAAATTGTTTTTGCCGATGGGGAAGGTGAGGCGTATT
TCAGCGGCATGCTGGCGTTTAATCGCGAAGTGAATGCCCAGGAGGTCGACCCCGCCTTTATTGCCGCCGTGCGTAAACGC
CTGAAGCTGAATCAGGCGCAGGCCGCCGAGTTTTTTGGCGGGGGAGCAAATGCATTCAGCCGCTATGAAACGGGGCGCAT
TGCCCCCCCTCGGCCGCTGATCCTGCTGTTTAAAGCGCTGGATAAACACCCTGAGCTTTTTGACGAGCTCAAAACGAGTT
AA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References