Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1080806..1081194 Replicon chromosome
Accession NZ_CP009450
Organism Pluralibacter gergoviae strain FB2

Toxin (Protein)


Gene name mqsR Uniprot ID A0A1S2B9G4
Locus tag LG71_RS05055 Protein ID WP_048254840.1
Coordinates 1080806..1081066 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag LG71_RS27725 Protein ID WP_199533721.1
Coordinates 1081069..1081194 (+) Length 42 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LG71_RS05040 1076812..1078764 + 1953 WP_043081596.1 glycoside hydrolase family 3 protein -
LG71_RS05045 1078807..1079616 - 810 WP_043081597.1 dienelactone hydrolase family protein -
LG71_RS05050 1079871..1080632 + 762 WP_043081598.1 uridine phosphorylase -
LG71_RS05055 1080806..1081066 + 261 WP_048254840.1 type II toxin-antitoxin system MqsR family toxin Toxin
LG71_RS27725 1081069..1081194 + 126 WP_199533721.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
LG71_RS05060 1081198..1081470 + 273 WP_199533722.1 type II toxin-antitoxin system MqsA family antitoxin -
LG71_RS05065 1081540..1082943 + 1404 WP_043081600.1 DNA recombination protein RmuC -
LG71_RS05070 1083019..1083774 + 756 WP_043081601.1 bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE -
LG71_RS05075 1083787..1084392 + 606 WP_043081602.1 SCP2 domain-containing protein -
LG71_RS05080 1084389..1086029 + 1641 WP_043081603.1 ubiquinone biosynthesis regulatory protein kinase UbiB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-85)

Antitoxin

Antitoxin MqsA/HigA-2

(1-41)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9824.42 Da        Isoelectric Point: 10.4380

>T49000 WP_048254840.1 NZ_CP009450:1080806-1081066 [Pluralibacter gergoviae]
MVSQGKLRVTANAFDGAALLGFSFPLAVSIASLINSLKPYDFYKSRTAYHDRTIWHDVYRVGRHQRQIYLKLIVQGDVLI
VSLKER

Download         Length: 261 bp

>T49000 NZ_CP009450:1080806-1081066 [Pluralibacter gergoviae]
ATGGTGTCTCAGGGTAAATTGAGGGTAACTGCAAACGCTTTCGACGGTGCCGCCTTACTCGGGTTTAGCTTTCCCTTAGC
CGTCAGTATTGCCAGTCTTATCAACTCCCTGAAACCTTATGACTTTTATAAAAGCAGGACTGCTTATCACGATCGCACAA
TCTGGCATGATGTTTATCGCGTTGGCCGGCATCAGCGACAAATCTATTTGAAGCTGATTGTGCAGGGGGATGTACTCATT
GTGTCCCTGAAGGAGCGATAA

Antitoxin


Download         Length: 42 a.a.        Molecular weight: 4523.16 Da        Isoelectric Point: 6.0215

>AT49000 WP_199533721.1 NZ_CP009450:1081069-1081194 [Pluralibacter gergoviae]
MKCPFCGSSVLKTETRDVIRAYKDQNTTIYALTGDFCDACG

Download         Length: 126 bp

>AT49000 NZ_CP009450:1081069-1081194 [Pluralibacter gergoviae]
ATGAAATGCCCTTTTTGCGGCAGCAGCGTTCTGAAGACGGAAACCAGAGATGTTATCCGCGCGTACAAAGATCAGAACAC
CACAATTTATGCGTTAACAGGCGATTTCTGTGACGCCTGCGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1S2B9G4

Antitoxin

Source ID Structure

References