Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2181491..2181688 Replicon chromosome
Accession NZ_CP009361
Organism Staphylococcus aureus strain ATCC 25923

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag KQ76_RS10960 Protein ID WP_073392962.1
Coordinates 2181584..2181688 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2181491..2181529 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQ76_RS10940 2177666..2178331 - 666 WP_001024099.1 SDR family oxidoreductase -
KQ76_RS10945 2178483..2178803 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
KQ76_RS10950 2178805..2179785 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
KQ76_RS10955 2180051..2181142 + 1092 WP_000495684.1 hypothetical protein -
- 2181491..2181529 + 39 - - Antitoxin
KQ76_RS10960 2181584..2181688 - 105 WP_073392962.1 hypothetical protein Toxin
KQ76_RS14695 2182368..2182526 + 159 WP_001792784.1 hypothetical protein -
KQ76_RS10965 2183185..2184042 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
KQ76_RS10970 2184110..2184892 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T48802 WP_073392962.1 NZ_CP009361:c2181688-2181584 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T48802 NZ_CP009361:c2181688-2181584 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT48802 NZ_CP009361:2181491-2181529 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References