Detailed information of TA system TA048795

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1880850..1881030
• Replicon: chromosome
• Accession: NZ_CP009361
• Organism: Staphylococcus aureus strain ATCC 25923

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: KQ76_RS14960
• Protein ID: WP_001801861.1
• Coordinates: 1880850..1880945 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1880973..1881030 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KQ76_RS09180	1875994..1876620	+	627	WP_000669038.1	hypothetical protein	-
KQ76_RS09185	1876661..1877005	+	345	WP_000627550.1	DUF3969 family protein	-
KQ76_RS09190	1877103..1877675	+	573	Protein_1773	hypothetical protein	-
KQ76_RS09195	1877824..1879191	-	1368	WP_001093574.1	FRG domain-containing protein	-
KQ76_RS09200	1879191..1879760	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
KQ76_RS09205	1879953..1880399	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
KQ76_RS14960	1880850..1880945	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1880973..1881030	-	58	-	-	Antitoxin
KQ76_RS09210	1881068..1881169	+	102	WP_001791232.1	hypothetical protein	-
KQ76_RS09215	1881344..1881787	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
KQ76_RS09220	1881787..1882230	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
KQ76_RS14585	1882230..1882672	-	443	Protein_1781	DUF1433 domain-containing protein	-
KQ76_RS09230	1883197..1885606	+	2410	Protein_1782	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T48795 WP_001801861.1 NZ_CP009361:1880850-1880945 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T48795 NZ_CP009361:1880850-1880945 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT48795 NZ_CP009361:c1881030-1880973 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin