Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
Location | 420914..421638 | Replicon | chromosome |
Accession | NZ_CP009125 | ||
Organism | Pectobacterium atrosepticum strain 21A |
Toxin (Protein)
Gene name | higB | Uniprot ID | Q6DA89 |
Locus tag | GZ59_RS01920 | Protein ID | WP_011091996.1 |
Coordinates | 420914..421225 (+) | Length | 104 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | GZ59_RS01925 | Protein ID | WP_011091997.1 |
Coordinates | 421222..421638 (+) | Length | 139 a.a. |
Genomic Context
Location: 420203..420754 (552 bp)
Type: Others
Protein ID: WP_039294652.1
Type: Others
Protein ID: WP_039294652.1
Location: 420914..421225 (312 bp)
Type: Toxin
Protein ID: WP_011091996.1
Type: Toxin
Protein ID: WP_011091996.1
Location: 421222..421638 (417 bp)
Type: Antitoxin
Protein ID: WP_011091997.1
Type: Antitoxin
Protein ID: WP_011091997.1
Location: 421841..422299 (459 bp)
Type: Others
Protein ID: WP_011091998.1
Type: Others
Protein ID: WP_011091998.1
Location: 425210..425656 (447 bp)
Type: Others
Protein ID: WP_011092001.1
Type: Others
Protein ID: WP_011092001.1
Location: 425666..426160 (495 bp)
Type: Others
Protein ID: WP_011092002.1
Type: Others
Protein ID: WP_011092002.1
Location: 417070..418605 (1536 bp)
Type: Others
Protein ID: WP_011091993.1
Type: Others
Protein ID: WP_011091993.1
Location: 418796..419731 (936 bp)
Type: Others
Protein ID: WP_011091994.1
Type: Others
Protein ID: WP_011091994.1
Location: 422390..423742 (1353 bp)
Type: Others
Protein ID: WP_011091999.1
Type: Others
Protein ID: WP_011091999.1
Location: 423776..425056 (1281 bp)
Type: Others
Protein ID: WP_011092000.1
Type: Others
Protein ID: WP_011092000.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GZ59_RS01905 | 417070..418605 | - | 1536 | WP_011091993.1 | carbohydrate porin | - |
GZ59_RS01910 | 418796..419731 | - | 936 | WP_011091994.1 | aminoimidazole riboside kinase | - |
GZ59_RS01915 | 420203..420754 | + | 552 | WP_039294652.1 | polymer-forming cytoskeletal protein | - |
GZ59_RS01920 | 420914..421225 | + | 312 | WP_011091996.1 | type II toxin-antitoxin system HigB family toxin | Toxin |
GZ59_RS01925 | 421222..421638 | + | 417 | WP_011091997.1 | helix-turn-helix domain-containing protein | Antitoxin |
GZ59_RS01930 | 421841..422299 | + | 459 | WP_011091998.1 | hypothetical protein | - |
GZ59_RS01935 | 422390..423742 | - | 1353 | WP_011091999.1 | aspartate aminotransferase family protein | - |
GZ59_RS01940 | 423776..425056 | - | 1281 | WP_011092000.1 | MFS transporter | - |
GZ59_RS01945 | 425210..425656 | + | 447 | WP_011092001.1 | helix-turn-helix transcriptional regulator | - |
GZ59_RS01950 | 425666..426160 | + | 495 | WP_011092002.1 | YhbP family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 a.a. Molecular weight: 12431.33 Da Isoelectric Point: 10.0380
>T48430 WP_011091996.1 NZ_CP009125:420914-421225 [Pectobacterium atrosepticum]
MHVISRAPFDAATNQFPNQAVALADLYRVIKREMYATPEDMKKRFPSLDRMKYREKWWVIDIGGGHLRVMFFADFERGKI
FIKHITSHAEYDRLTEYYRRNKE
MHVISRAPFDAATNQFPNQAVALADLYRVIKREMYATPEDMKKRFPSLDRMKYREKWWVIDIGGGHLRVMFFADFERGKI
FIKHITSHAEYDRLTEYYRRNKE
Download Length: 312 bp
>T48430 NZ_CP009125:420914-421225 [Pectobacterium atrosepticum]
ATGCATGTGATTTCGCGCGCACCTTTTGATGCTGCAACCAACCAGTTTCCGAATCAGGCGGTAGCACTCGCTGACCTATA
TCGGGTTATAAAACGCGAAATGTATGCAACGCCGGAGGATATGAAAAAACGCTTTCCCAGCTTAGATAGGATGAAATATC
GAGAAAAGTGGTGGGTTATTGATATCGGTGGTGGGCATCTTCGAGTGATGTTTTTTGCTGATTTTGAGCGAGGGAAAATC
TTCATCAAGCACATAACATCCCATGCAGAGTACGACAGGCTGACAGAGTATTACCGGAGGAATAAAGAATGA
ATGCATGTGATTTCGCGCGCACCTTTTGATGCTGCAACCAACCAGTTTCCGAATCAGGCGGTAGCACTCGCTGACCTATA
TCGGGTTATAAAACGCGAAATGTATGCAACGCCGGAGGATATGAAAAAACGCTTTCCCAGCTTAGATAGGATGAAATATC
GAGAAAAGTGGTGGGTTATTGATATCGGTGGTGGGCATCTTCGAGTGATGTTTTTTGCTGATTTTGAGCGAGGGAAAATC
TTCATCAAGCACATAACATCCCATGCAGAGTACGACAGGCTGACAGAGTATTACCGGAGGAATAAAGAATGA
Antitoxin
Download Length: 139 a.a. Molecular weight: 15395.73 Da Isoelectric Point: 4.7943
>AT48430 WP_011091997.1 NZ_CP009125:421222-421638 [Pectobacterium atrosepticum]
MMYADAIKAANDLTSIVPFLGGSTSRKDYEDALKLTEYLIESEPDSSLIDMLTAKIDKYENEAPEFAAFNERIKALPAGI
ALLRVLMDQHQLMQSDFEAEIGKKSLVSRILNGERTLTLAHMRALAKRFNIPVSAFVD
MMYADAIKAANDLTSIVPFLGGSTSRKDYEDALKLTEYLIESEPDSSLIDMLTAKIDKYENEAPEFAAFNERIKALPAGI
ALLRVLMDQHQLMQSDFEAEIGKKSLVSRILNGERTLTLAHMRALAKRFNIPVSAFVD
Download Length: 417 bp
>AT48430 NZ_CP009125:421222-421638 [Pectobacterium atrosepticum]
ATGATGTATGCAGATGCCATCAAGGCAGCTAACGATCTGACGAGTATCGTACCGTTCCTCGGGGGCAGCACCTCTCGTAA
GGATTATGAGGATGCACTGAAACTCACTGAATATCTGATCGAGAGTGAGCCTGATAGTTCGCTAATCGATATGCTGACTG
CCAAAATTGATAAATACGAAAATGAGGCGCCGGAGTTTGCAGCCTTCAACGAACGTATTAAAGCACTCCCTGCCGGTATC
GCTTTGCTACGTGTCCTCATGGATCAGCACCAGCTAATGCAGAGTGATTTTGAAGCTGAGATCGGTAAAAAGTCTCTGGT
ATCCCGTATTCTAAACGGTGAGCGTACGTTAACACTTGCTCATATGAGAGCTCTCGCTAAGCGATTCAATATTCCCGTGA
GTGCTTTTGTTGATTAA
ATGATGTATGCAGATGCCATCAAGGCAGCTAACGATCTGACGAGTATCGTACCGTTCCTCGGGGGCAGCACCTCTCGTAA
GGATTATGAGGATGCACTGAAACTCACTGAATATCTGATCGAGAGTGAGCCTGATAGTTCGCTAATCGATATGCTGACTG
CCAAAATTGATAAATACGAAAATGAGGCGCCGGAGTTTGCAGCCTTCAACGAACGTATTAAAGCACTCCCTGCCGGTATC
GCTTTGCTACGTGTCCTCATGGATCAGCACCAGCTAATGCAGAGTGATTTTGAAGCTGAGATCGGTAAAAAGTCTCTGGT
ATCCCGTATTCTAAACGGTGAGCGTACGTTAACACTTGCTCATATGAGAGCTCTCGCTAAGCGATTCAATATTCCCGTGA
GTGCTTTTGTTGATTAA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | Q6DA89 |
Antitoxin
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Source | ID | Structure |
---|---|---|
No matching records found |