Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 420914..421638 Replicon chromosome
Accession NZ_CP009125
Organism Pectobacterium atrosepticum strain 21A

Toxin (Protein)


Gene name higB Uniprot ID Q6DA89
Locus tag GZ59_RS01920 Protein ID WP_011091996.1
Coordinates 420914..421225 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag GZ59_RS01925 Protein ID WP_011091997.1
Coordinates 421222..421638 (+) Length 139 a.a.

Genomic Context


GZ59_RS01915GZ59_RS01920GZ59_RS01925GZ59_RS01930GZ59_RS01945GZ59_RS01950GZ59_RS01905GZ59_RS01910GZ59_RS01935GZ59_RS01940
Location: 420203..420754 (552 bp)
Type: Others
Protein ID: WP_039294652.1
Location: 420914..421225 (312 bp)
Type: Toxin
Protein ID: WP_011091996.1
Location: 421222..421638 (417 bp)
Type: Antitoxin
Protein ID: WP_011091997.1
Location: 421841..422299 (459 bp)
Type: Others
Protein ID: WP_011091998.1
Location: 425210..425656 (447 bp)
Type: Others
Protein ID: WP_011092001.1
Location: 425666..426160 (495 bp)
Type: Others
Protein ID: WP_011092002.1
Location: 417070..418605 (1536 bp)
Type: Others
Protein ID: WP_011091993.1
Location: 418796..419731 (936 bp)
Type: Others
Protein ID: WP_011091994.1
Location: 422390..423742 (1353 bp)
Type: Others
Protein ID: WP_011091999.1
Location: 423776..425056 (1281 bp)
Type: Others
Protein ID: WP_011092000.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GZ59_RS01905417070..418605-1536WP_011091993.1carbohydrate porin-
GZ59_RS01910418796..419731-936WP_011091994.1aminoimidazole riboside kinase-
GZ59_RS01915420203..420754+552WP_039294652.1polymer-forming cytoskeletal protein-
GZ59_RS01920420914..421225+312WP_011091996.1type II toxin-antitoxin system HigB family toxinToxin
GZ59_RS01925421222..421638+417WP_011091997.1helix-turn-helix domain-containing proteinAntitoxin
GZ59_RS01930421841..422299+459WP_011091998.1hypothetical protein-
GZ59_RS01935422390..423742-1353WP_011091999.1aspartate aminotransferase family protein-
GZ59_RS01940423776..425056-1281WP_011092000.1MFS transporter-
GZ59_RS01945425210..425656+447WP_011092001.1helix-turn-helix transcriptional regulator-
GZ59_RS01950425666..426160+495WP_011092002.1YhbP family protein-

Associated MGEs


Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 104 a.a.        Molecular weight: 12431.33 Da        Isoelectric Point: 10.0380

>T48430 WP_011091996.1 NZ_CP009125:420914-421225 [Pectobacterium atrosepticum]
MHVISRAPFDAATNQFPNQAVALADLYRVIKREMYATPEDMKKRFPSLDRMKYREKWWVIDIGGGHLRVMFFADFERGKI
FIKHITSHAEYDRLTEYYRRNKE

Download         Length: 312 bp

>T48430 NZ_CP009125:420914-421225 [Pectobacterium atrosepticum]
ATGCATGTGATTTCGCGCGCACCTTTTGATGCTGCAACCAACCAGTTTCCGAATCAGGCGGTAGCACTCGCTGACCTATA
TCGGGTTATAAAACGCGAAATGTATGCAACGCCGGAGGATATGAAAAAACGCTTTCCCAGCTTAGATAGGATGAAATATC
GAGAAAAGTGGTGGGTTATTGATATCGGTGGTGGGCATCTTCGAGTGATGTTTTTTGCTGATTTTGAGCGAGGGAAAATC
TTCATCAAGCACATAACATCCCATGCAGAGTACGACAGGCTGACAGAGTATTACCGGAGGAATAAAGAATGA

Antitoxin


Download         Length: 139 a.a.        Molecular weight: 15395.73 Da        Isoelectric Point: 4.7943

>AT48430 WP_011091997.1 NZ_CP009125:421222-421638 [Pectobacterium atrosepticum]
MMYADAIKAANDLTSIVPFLGGSTSRKDYEDALKLTEYLIESEPDSSLIDMLTAKIDKYENEAPEFAAFNERIKALPAGI
ALLRVLMDQHQLMQSDFEAEIGKKSLVSRILNGERTLTLAHMRALAKRFNIPVSAFVD

Download         Length: 417 bp

>AT48430 NZ_CP009125:421222-421638 [Pectobacterium atrosepticum]
ATGATGTATGCAGATGCCATCAAGGCAGCTAACGATCTGACGAGTATCGTACCGTTCCTCGGGGGCAGCACCTCTCGTAA
GGATTATGAGGATGCACTGAAACTCACTGAATATCTGATCGAGAGTGAGCCTGATAGTTCGCTAATCGATATGCTGACTG
CCAAAATTGATAAATACGAAAATGAGGCGCCGGAGTTTGCAGCCTTCAACGAACGTATTAAAGCACTCCCTGCCGGTATC
GCTTTGCTACGTGTCCTCATGGATCAGCACCAGCTAATGCAGAGTGATTTTGAAGCTGAGATCGGTAAAAAGTCTCTGGT
ATCCCGTATTCTAAACGGTGAGCGTACGTTAACACTTGCTCATATGAGAGCTCTCGCTAAGCGATTCAATATTCCCGTGA
GTGCTTTTGTTGATTAA

Similar Proteins


Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBQ6DA89


Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References