Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3776997..3777219 Replicon chromosome
Accession NZ_CP008801
Organism Escherichia coli KLY

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag HQ24_RS23460 Protein ID WP_000141634.1
Coordinates 3776997..3777104 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3777153..3777219 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HQ24_RS18745 3772250..3773002 - 753 Protein_3564 cellulose biosynthesis protein BcsQ -
HQ24_RS18750 3773014..3773202 - 189 WP_001063318.1 YhjR family protein -
HQ24_RS18755 3773475..3775046 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
HQ24_RS18760 3775043..3775234 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
HQ24_RS18765 3775231..3776910 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
HQ24_RS23460 3776997..3777104 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3777153..3777219 + 67 - - Antitoxin
HQ24_RS18780 3777580..3778851 + 1272 WP_001295225.1 transporter -
HQ24_RS18785 3778881..3779885 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
HQ24_RS18790 3779882..3780865 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
HQ24_RS18795 3780876..3781778 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T47527 WP_000141634.1 NZ_CP008801:c3777104-3776997 [Escherichia coli KLY]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T47527 NZ_CP008801:c3777104-3776997 [Escherichia coli KLY]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT47527 NZ_CP008801:3777153-3777219 [Escherichia coli KLY]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References