Detailed information of TA system TA047297

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2646321..2646482
• Replicon: chromosome
• Accession: NZ_CP008724
• Organism: Staphylococcus xylosus strain SMQ-121

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SXYLSMQ121_RS13045
• Protein ID: WP_002441941.1
• Coordinates: 2646387..2646482 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2646321..2646358 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SXYLSMQ121_RS12325	2641342..2641806	+	465	WP_042363441.1	hypothetical protein	-
SXYLSMQ121_RS12330	2642006..2642314	-	309	WP_107543257.1	hypothetical protein	-
SXYLSMQ121_RS12335	2642477..2643169	+	693	WP_171031833.1	hypothetical protein	-
SXYLSMQ121_RS13040	2643355..2643441	-	87	WP_107539440.1	type I toxin-antitoxin system Fst family toxin	-
SXYLSMQ121_RS12340	2643777..2644739	-	963	WP_042363443.1	nitronate monooxygenase	-
SXYLSMQ121_RS12345	2644864..2645235	+	372	WP_042363444.1	helix-turn-helix transcriptional regulator	-
SXYLSMQ121_RS12350	2645409..2646134	+	726	WP_042363445.1	NAD(P)-binding domain-containing protein	-
-	2646321..2646358	+	38	NuclAT_2	-	Antitoxin
SXYLSMQ121_RS13045	2646387..2646482	-	96	WP_002441941.1	type I toxin-antitoxin system Fst family toxin	Toxin
SXYLSMQ121_RS12355	2646617..2647792	-	1176	WP_042363446.1	ABC transporter permease	-
SXYLSMQ121_RS12360	2647789..2648469	-	681	WP_042363447.1	ABC transporter ATP-binding protein	-
SXYLSMQ121_RS12365	2648466..2649581	-	1116	WP_042363448.1	RND transporter	-
SXYLSMQ121_RS12370	2650002..2651375	+	1374	WP_052344191.1	YfcC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (15-90)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3560.34 Da
• Isoelectric Point: 9.9256

>T47297 WP_002441941.1 NZ_CP008724:c2646482-2646387 [Staphylococcus xylosus]
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK

Nucleotide

• Length: 96 bp

>T47297 NZ_CP008724:c2646482-2646387 [Staphylococcus xylosus]
ATGCTTATGATCTTCGTTCACATCATTGCACCAGTCATTAGTGGCTGTGCAGTTGCGTACTTTACTTACTGGCTTAGTAG
TAAACGCAATAAATAG

Antitoxin

Nucleotide

• Length: 38 bp

>AT47297 NZ_CP008724:2646321-2646358 [Staphylococcus xylosus]
TATGCACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin