Detailed information of TA system TA047295

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1788816..1789075
• Replicon: chromosome
• Accession: NZ_CP008724
• Organism: Staphylococcus xylosus strain SMQ-121

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: SXYLSMQ121_RS12885
• Protein ID: WP_080706852.1
• Coordinates: 1788968..1789075 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	1788816..1788978 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SXYLSMQ121_RS08380	1784062..1785945	-	1884	WP_042362894.1	glycosyltransferase	-
SXYLSMQ121_RS08385	1786467..1786715	-	249	WP_042362895.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
SXYLSMQ121_RS13020	1787818..1787982	-	165	WP_155266933.1	hypothetical protein	-
-	1788816..1788978	+	163	NuclAT_0	-	Antitoxin
-	1788845..1788978	+	134	NuclAT_1	-	-
-	1788853..1788909	+	57	NuclAT_3	-	-
-	1788853..1788909	+	57	NuclAT_4	-	-
SXYLSMQ121_RS12885	1788968..1789075	-	108	WP_080706852.1	putative holin-like toxin	Toxin
SXYLSMQ121_RS08395	1790676..1791185	-	510	WP_042362896.1	metallophosphoesterase	-
SXYLSMQ121_RS08400	1791185..1791766	-	582	WP_042362897.1	XTP/dITP diphosphatase	-
SXYLSMQ121_RS08405	1791778..1792578	-	801	WP_029379028.1	glutamate racemase	-
SXYLSMQ121_RS08410	1792786..1793598	-	813	WP_029379029.1	succinate dehydrogenase iron-sulfur subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3786.79 Da
• Isoelectric Point: 10.4997

>T47295 WP_080706852.1 NZ_CP008724:c1789075-1788968 [Staphylococcus xylosus]
VVSIVEALHLMLGFGTFIVTLLGLVIAIVKLIHKK

Nucleotide

• Length: 108 bp

>T47295 NZ_CP008724:c1789075-1788968 [Staphylococcus xylosus]
GTGGTTTCAATTGTAGAAGCGCTACACTTAATGTTAGGTTTCGGTACTTTCATCGTTACCTTATTAGGTTTAGTTATCGC
AATTGTTAAATTAATCCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 163 bp

>AT47295 NZ_CP008724:1788816-1788978 [Staphylococcus xylosus]
TTGATAATATTTTTATGTTGTGTTAATTTATAGATAGAAAAAGGGCAACACACCATAAGTGTATCGCCCTAATGAGCCCG
TTAAAAAGACGGTGGCTAGTTACTAATAATTATCAAAAAATAATCATCGAAACCGGCCAAAGTTAGCGATGGTTATTTTT
TAT

Structures

Antitoxin