Detailed information of TA system TA047210

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 41208..41797
• Replicon: chromosome
• Accession: NZ_CP007810
• Organism: Xanthomonas oryzae pv. oryzicola strain YM15

Toxin (Protein)

• Gene name: graT
• Uniprot ID: A0A0C5V8F2
• Locus tag: FE36_RS00190
• Protein ID: WP_024712137.1
• Coordinates: 41516..41797 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: FE36_RS00185
• Protein ID: WP_011260746.1
• Coordinates: 41208..41498 (-)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FE36_RS00160	36507..36983	-	477	WP_047339412.1	DUF4123 domain-containing protein	-
FE36_RS00165	36986..37420	-	435	WP_071162385.1	PAAR domain-containing protein	-
FE36_RS19710	37558..37782	-	225	WP_044751358.1	hypothetical protein	-
FE36_RS00175	38118..38450	+	333	WP_011260743.1	hypothetical protein	-
FE36_RS00180	38901..40295	-	1395	WP_024712138.1	nucleoside hydrolase	-
FE36_RS00185	41208..41498	-	291	WP_011260746.1	HigA family addiction module antidote protein	Antitoxin
FE36_RS00190	41516..41797	-	282	WP_024712137.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FE36_RS00195	41892..44153	-	2262	WP_047339413.1	exodeoxyribonuclease V subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-1 (4-93)

Antitoxin

• Cro/C1-type helix-turn-helix domain (14-68)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 11125.91 Da
• Isoelectric Point: 10.5318

>T47210 WP_024712137.1 NZ_CP007810:c41797-41516 [Xanthomonas oryzae pv. oryzicola]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQRRGQYNIRINDQWRICFRWM
EGDVVQVEIVDYH

Nucleotide

• Length: 282 bp

>T47210 NZ_CP007810:c41797-41516 [Xanthomonas oryzae pv. oryzicola]
ATGATCAGGAGCTTTATCGACAAGGACGCCGAAAAGATCTGGCTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCA
ATTGGTCGCGCGCCGCAAGTTGCGCATGCTCAATGCCGCCGCGCATCTCGACGATCTGCGGATCCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCCAGCGGCGCGGCCAGTACAACATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATG
GAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10420.07 Da
• Isoelectric Point: 7.2040

>AT47210 WP_011260746.1 NZ_CP007810:c41498-41208 [Xanthomonas oryzae pv. oryzicola]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Nucleotide

• Length: 291 bp

>AT47210 NZ_CP007810:c41498-41208 [Xanthomonas oryzae pv. oryzicola]
ATGACGGTCCTACCCAATATCCATCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTGGGCCTGCAGGCCGACTACGAGCTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA

Structures

Toxin

• AlphaFold DB: A0A0C5V8F2