Detailed information of TA system TA047060

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2042651..2042897
• Replicon: chromosome
• Accession: NZ_CP007800
• Organism: Bacillus subtilis subsp. subtilis str. JH642 substr. AG174 strain JH642

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: BSUA_RS23100
• Protein ID: WP_109789044.1
• Coordinates: 2042651..2042743 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2042724..2042897 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BSUA_RS10385	2037810..2038145	+	336	WP_009967409.1	hypothetical protein	-
BSUA_RS10390	2038192..2041797	-	3606	WP_004399367.1	membrane protein	-
BSUA_RS10395	2042030..2042362	-	333	WP_026009814.1	hypothetical protein	-
BSUA_RS23100	2042651..2042743	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2042724..2042897	-	174	-	-	Antitoxin
BSUA_RS10400	2043012..2043854	-	843	WP_003231327.1	hypothetical protein	-
BSUA_RS10405	2044054..2044512	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
BSUA_RS10410	2044522..2046324	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
BSUA_RS10415	2046426..2046983	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2028636..2052314	23678

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T47060 WP_109789044.1 NZ_CP007800:2042651-2042743 [Bacillus subtilis subsp. subtilis str. JH642 substr. AG174]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T47060 NZ_CP007800:2042651-2042743 [Bacillus subtilis subsp. subtilis str. JH642 substr. AG174]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA

Antitoxin

Nucleotide

• Length: 174 bp

>AT47060 NZ_CP007800:c2042897-2042724 [Bacillus subtilis subsp. subtilis str. JH642 substr. AG174]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin