Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1901058..1901240 Replicon chromosome
Accession NZ_CP007676
Organism Staphylococcus aureus strain HUV05

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag ER12_RS15785 Protein ID WP_001801861.1
Coordinates 1901058..1901153 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1901181..1901240 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ER12_RS09395 1896718..1897344 + 627 WP_000669046.1 hypothetical protein -
ER12_RS09400 1897385..1897729 + 345 WP_000627551.1 DUF3969 family protein -
ER12_RS09405 1897827..1898378 + 552 WP_000414205.1 hypothetical protein -
ER12_RS09410 1898596..1899237 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
ER12_RS09415 1899351..1899536 - 186 WP_000809857.1 hypothetical protein -
ER12_RS09420 1899538..1899714 - 177 WP_000375476.1 hypothetical protein -
ER12_RS09425 1899725..1900108 - 384 WP_000070811.1 hypothetical protein -
ER12_RS09435 1900712..1900855 - 144 WP_001549059.1 transposase -
ER12_RS15785 1901058..1901153 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1901181..1901240 - 60 - - Antitoxin
ER12_RS09440 1901276..1901377 + 102 WP_001791893.1 hypothetical protein -
ER12_RS15315 1901355..1901531 - 177 Protein_1813 transposase -
ER12_RS09445 1901725..1902102 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1894158..1918016 23858


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T46871 WP_001801861.1 NZ_CP007676:1901058-1901153 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T46871 NZ_CP007676:1901058-1901153 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT46871 NZ_CP007676:c1901240-1901181 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References