Detailed information of TA system TA046871

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1901058..1901240
• Replicon: chromosome
• Accession: NZ_CP007676
• Organism: Staphylococcus aureus strain HUV05

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: ER12_RS15785
• Protein ID: WP_001801861.1
• Coordinates: 1901058..1901153 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1901181..1901240 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ER12_RS09395	1896718..1897344	+	627	WP_000669046.1	hypothetical protein	-
ER12_RS09400	1897385..1897729	+	345	WP_000627551.1	DUF3969 family protein	-
ER12_RS09405	1897827..1898378	+	552	WP_000414205.1	hypothetical protein	-
ER12_RS09410	1898596..1899237	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
ER12_RS09415	1899351..1899536	-	186	WP_000809857.1	hypothetical protein	-
ER12_RS09420	1899538..1899714	-	177	WP_000375476.1	hypothetical protein	-
ER12_RS09425	1899725..1900108	-	384	WP_000070811.1	hypothetical protein	-
ER12_RS09435	1900712..1900855	-	144	WP_001549059.1	transposase	-
ER12_RS15785	1901058..1901153	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1901181..1901240	-	60	-	-	Antitoxin
ER12_RS09440	1901276..1901377	+	102	WP_001791893.1	hypothetical protein	-
ER12_RS15315	1901355..1901531	-	177	Protein_1813	transposase	-
ER12_RS09445	1901725..1902102	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1894158..1918016	23858

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T46871 WP_001801861.1 NZ_CP007676:1901058-1901153 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T46871 NZ_CP007676:1901058-1901153 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT46871 NZ_CP007676:c1901240-1901181 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin