Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2230923..2231186 Replicon chromosome
Accession NZ_CP007674
Organism Staphylococcus aureus strain CA15

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag EQ90_RS16050 Protein ID WP_001802298.1
Coordinates 2231082..2231186 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2230923..2231087 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EQ90_RS11385 2227106..2227771 - 666 WP_047339388.1 SDR family oxidoreductase -
EQ90_RS11390 2227923..2228243 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
EQ90_RS11395 2228245..2229225 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
EQ90_RS11400 2229491..2230582 + 1092 WP_000495671.1 lytic regulatory protein -
- 2230923..2231087 + 165 - - Antitoxin
EQ90_RS16050 2231082..2231186 - 105 WP_001802298.1 hypothetical protein Toxin
EQ90_RS16620 2231347..2231830 - 484 Protein_2160 recombinase family protein -
EQ90_RS11415 2231873..2233009 - 1137 WP_000115564.1 SAP domain-containing protein -
EQ90_RS16055 2233298..2233390 + 93 WP_001790138.1 hypothetical protein -
EQ90_RS11425 2234095..2234952 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
EQ90_RS11430 2235020..2235802 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T46864 WP_001802298.1 NZ_CP007674:c2231186-2231082 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T46864 NZ_CP007674:c2231186-2231082 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT46864 NZ_CP007674:2230923-2231087 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References