Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1895457..1895639 Replicon chromosome
Accession NZ_CP007674
Organism Staphylococcus aureus strain CA15

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag EQ90_RS16595 Protein ID WP_001801861.1
Coordinates 1895457..1895552 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1895580..1895639 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EQ90_RS09360 1891117..1891743 + 627 WP_000669046.1 hypothetical protein -
EQ90_RS09365 1891784..1892128 + 345 WP_000627551.1 DUF3969 family protein -
EQ90_RS09370 1892226..1892777 + 552 WP_000414205.1 hypothetical protein -
EQ90_RS09375 1892995..1893636 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
EQ90_RS09380 1893750..1893935 - 186 WP_000809857.1 hypothetical protein -
EQ90_RS15745 1893937..1894113 - 177 WP_000375476.1 hypothetical protein -
EQ90_RS09390 1894124..1894507 - 384 WP_000070811.1 hypothetical protein -
EQ90_RS15755 1895111..1895254 - 144 WP_001549059.1 transposase -
EQ90_RS16595 1895457..1895552 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1895580..1895639 - 60 - - Antitoxin
EQ90_RS15760 1895675..1895776 + 102 WP_001791893.1 hypothetical protein -
EQ90_RS15765 1895754..1895930 - 177 Protein_1809 transposase -
EQ90_RS09410 1896124..1896501 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA 1858017..1976303 118286


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T46855 WP_001801861.1 NZ_CP007674:1895457-1895552 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T46855 NZ_CP007674:1895457-1895552 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT46855 NZ_CP007674:c1895639-1895580 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References