Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1898585..1898767 Replicon chromosome
Accession NZ_CP007672
Organism Staphylococcus aureus strain CA12

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag EQ80_RS15465 Protein ID WP_001801861.1
Coordinates 1898585..1898680 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1898708..1898767 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EQ80_RS09390 1894245..1894871 + 627 WP_000669046.1 hypothetical protein -
EQ80_RS09395 1894912..1895256 + 345 WP_000627551.1 DUF3969 family protein -
EQ80_RS09400 1895354..1895905 + 552 WP_000414205.1 hypothetical protein -
EQ80_RS09405 1896123..1896764 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
EQ80_RS09410 1896878..1897063 - 186 WP_000809857.1 hypothetical protein -
EQ80_RS09415 1897065..1897241 - 177 WP_000375476.1 hypothetical protein -
EQ80_RS09420 1897252..1897635 - 384 WP_000070811.1 hypothetical protein -
EQ80_RS09430 1898239..1898382 - 144 WP_001549059.1 transposase -
EQ80_RS15465 1898585..1898680 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1898708..1898767 - 60 - - Antitoxin
EQ80_RS09435 1898803..1898904 + 102 WP_001791893.1 hypothetical protein -
EQ80_RS15085 1898882..1899058 - 177 Protein_1808 transposase -
EQ80_RS09440 1899252..1899629 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1891685..1918683 26998


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T46839 WP_001801861.1 NZ_CP007672:1898585-1898680 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T46839 NZ_CP007672:1898585-1898680 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT46839 NZ_CP007672:c1898767-1898708 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References