Detailed information of TA system TA046809

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2242036..2242253
• Replicon: chromosome
• Accession: NZ_CP007659
• Organism: Staphylococcus aureus strain H-EMRSA-15

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: ER16_RS11380
• Protein ID: WP_075583739.1
• Coordinates: 2242149..2242253 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2242036..2242091 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ER16_RS11360	2238092..2238757	-	666	WP_001024097.1	SDR family oxidoreductase	-
ER16_RS11365	2238909..2239229	+	321	WP_000003755.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
ER16_RS11370	2239231..2240211	+	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
ER16_RS11375	2240477..2241568	+	1092	WP_000495678.1	hypothetical protein	-
-	2242036..2242091	+	56	-	-	Antitoxin
ER16_RS11380	2242149..2242253	-	105	WP_075583739.1	hypothetical protein	Toxin
ER16_RS15005	2242351..2242512	-	162	Protein_2153	helix-turn-helix domain-containing protein	-
ER16_RS15340	2242930..2243088	+	159	WP_024928151.1	hypothetical protein	-
ER16_RS11390	2243748..2244605	-	858	WP_000370944.1	Cof-type HAD-IIB family hydrolase	-
ER16_RS11395	2244673..2245455	-	783	WP_000908181.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3861.73 Da
• Isoelectric Point: 7.0039

>T46809 WP_075583739.1 NZ_CP007659:c2242253-2242149 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Nucleotide

• Length: 105 bp

>T46809 NZ_CP007659:c2242253-2242149 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTAATCAAGGCCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT46809 NZ_CP007659:2242036-2242091 [Staphylococcus aureus]
AAAAAGGGCAACACTCAGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin