Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2242036..2242253 Replicon chromosome
Accession NZ_CP007659
Organism Staphylococcus aureus strain H-EMRSA-15

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag ER16_RS11380 Protein ID WP_075583739.1
Coordinates 2242149..2242253 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2242036..2242091 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ER16_RS11360 2238092..2238757 - 666 WP_001024097.1 SDR family oxidoreductase -
ER16_RS11365 2238909..2239229 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
ER16_RS11370 2239231..2240211 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
ER16_RS11375 2240477..2241568 + 1092 WP_000495678.1 hypothetical protein -
- 2242036..2242091 + 56 - - Antitoxin
ER16_RS11380 2242149..2242253 - 105 WP_075583739.1 hypothetical protein Toxin
ER16_RS15005 2242351..2242512 - 162 Protein_2153 helix-turn-helix domain-containing protein -
ER16_RS15340 2242930..2243088 + 159 WP_024928151.1 hypothetical protein -
ER16_RS11390 2243748..2244605 - 858 WP_000370944.1 Cof-type HAD-IIB family hydrolase -
ER16_RS11395 2244673..2245455 - 783 WP_000908181.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3861.73 Da        Isoelectric Point: 7.0039

>T46809 WP_075583739.1 NZ_CP007659:c2242253-2242149 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Download         Length: 105 bp

>T46809 NZ_CP007659:c2242253-2242149 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTAATCAAGGCCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT46809 NZ_CP007659:2242036-2242091 [Staphylococcus aureus]
AAAAAGGGCAACACTCAGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References